The zygomycete fungus Rhizomucor pusillus secretes an aspartic proteinase (MPP) that contains asparagine ( N )-linked oligosaccharides at two sites. Mutant strain 1116 defective in N -glycosylation secretes MPP with truncated oligo-saccharide chains. Lipid-linked oligosaccharides in mutant 1116 were labeled with [6-(3)H]glucosamine and [2-(3)H]mannose, prepared by cycles of solvent extraction, ...

Hyperbolic space groups are isometry groups, acting discontinuously on the hyperbolic 3-space with compact fundamental domain. One possibility to classify them is to look for fundamental domains of these groups. Here are considered supergroups for four series of groups with simplicial fundamental domains. Considered simplices, denoted in [9] by T19, T46, T59, belong to family F12, while T31 bel...

The feasiblity of using Yb2+ as a scintillation sensitiser for CsBa2I5:Sm2+ near-infrared scintillators has been assessed. CsBa2I5 samples with concentrations ranging from 0.3% to 2% and 0–1% Sm2+ have studied. properties determined the dynamics mechanism studied through photoluminescence measurements. Radiationless energy transfer between ions plays key role in increasing ratio spin-forbidden ...

background: although most studies on female-headed families focus on women's access to social support, the associations between social capital and quality of life in these families are unclear in many societies (such as iran). this study aimed to determine the associations between social capital and quality of life in iranian female headed families.   methods : this cross-sectional study was pe...

In the present article, we summarize the preclinical pharmacology of 4-{(R)-(3-aminophenyl)[4-(4-fluorobenzyl)-piperazin-1-yl]methyl}-N,N-diethylbenzamide (AZD2327), a highly potent and selective agonist of the δ-opioid receptor. AZD2327 binds with sub-nanomolar affinity to the human opioid receptor (K(i) = 0.49 and 0.75 nM at the C27 and F27 isoforms, respectively) and is highly selective (>10...

Aid to families with dependent children (AFDC) began with the Social Security Act, passed 50 years ago to provide what President Franklin D. Roosevelt called a “safeguard against misfortunes which cannot be wholly eliminated in this manmade world of ours. ” In creating the program, originally called aid to dependent children, the .Federal Government for the first time accepted responsibility fo...

Domains of unknown function (DUFs) are a large set of uncharacterized protein families that are found in the Pfam database. Here, the scale and growth of functionally uncharacterized families in biological databases are surveyed and the prospects for discovering their function are examined. In particular, the important role that structural genomics can play in identifying potential function is ...

We use the Rosetta de novo structure prediction method to produce three-dimensional structure models for all Pfam-A sequence families with average length under 150 residues and no link to any protein of known structure. To estimate the reliability of the predictions, the method was calibrated on 131 proteins of known structure. For approximately 60% of the proteins one of the top five models wa...