objective(s): nowadays much effort is being invested in order to diagnose the mechanisms involved in neural differentiation. by clarifying this, making desired neural cells in vitro and applying them into diverse neurological disorders suffered from neural cell malfunctions could be a feasible choice. thus, the present study assessed the capability of fetal brain extract (fbe) to induce rat bon...

Fetal MRI is an essential tool for analyzing morphological changes of fetal brain structure. The automated methods developed for adult brain extraction are unsuitable for fetal brain extraction because of the differences in tissue types and tissue properties between adult and fetal brain. However, only few automated fetal brain segmentation methods are available. In this paper we propose a full...

Introduction This study presents the first direct investigation of fetal brain activity in utero using fMRI. Human fetal brain activity is usually studied indirectly by monitoring the changes in fetal heart rate and associated fetal movements, although recently fetal MEG has been attempted’. fMRI offers a safe and relatively robust method of monitoring fetal brain activity. This has major impli...

background: the aim of this study was to apply the nested-pcr and bioassay methods in detection and genotyping of toxoplasma gondii infection in provided sheep aborted fetus samples from qazvin province of iran. methods : eighteen sheep aborted fetal samples were studied by nested-pcr-rflp, histopathologi­cal observation and microbiological assay. bioassay in mice was carried out by inoculating...

Fetal type posterior cerebral artery (FTPCA) is a variant of circulation brain, in which the distal part (PCA) perfused by branch internal carotid (ICA) via fetal communicating (fetal PCOM). In presence PCOM, paradoxical concurrent infarction anterior and may happen. We report 67-year-old man who presented with sudden onset right sided weakness aphasia, National Institutes Health Stroke Scale (...

Organoids derived from human pluripotent stem cells recapitulate the early three-dimensional organization of the human brain, but whether they establish the epigenomic and transcriptional programs essential for brain development is unknown. We compared epigenomic and regulatory features in cerebral organoids and human fetal brain, using genome-wide, base resolution DNA methylome and transcripto...

Maternal thyroid hormone (TH) crosses the placenta and is postulated to regulate fetal brain development. However, TH-dependent stages of fetal brain development remain to be characterised. We have therefore compared the levels of several neuronal and glial cytoskeletal proteins in fetal brains from normal (N) and partially thyroidectomised (TX) rat dams by immunoblotting. Pregnancies were stud...