BACKGROUND Congenital diaphragmatic hernia (CDH) with liver herniation and a lung area to head circumference ratio (LHR) < 1 [corrected] is associated with a high rate of neonatal death due to pulmonary hypoplasia. METHODS We report the development of a minimally invasive and reversible fetoscopic tracheal occlusion (FETO) with a balloon, carried out in 21 consecutive fetuses with severe CDH....

In order to achieve the purpose of high-efficiency dephosphorization by single-slag method during combined blown converter steelmaking process, CaO-SiO2-FetO-MgO-MnO-P2O5 slag system was taken as research object, and slag-forming route studied. The effects compositions on liquidus contour map phosphorus distribution ratios (recorded Lp) were calculated thermodynamics software FactSage, then the...

According to various authors1-3 vascular anastomosis is present in 85-100% of all monochorial placentae, and may allow the unbalanced transfer of blood from one twin to another. Such vascular communications may be obvious on inspection or on injection ofdye into the placental vessels. The most common anastomosis is of direct arterio-arterial type, but some are veno-venous. Perhaps of greater pa...

OBJECTIVES Sildenafil citrate, a specific phosphodiesterase-5 inhibitor, is increasingly used for pulmonary hypertension in pregnancy. Sildenafil is also emerging as a potential candidate for the treatment of intra-uterine growth retardation and for premature labor. Its effects in the feto-placental circulation are not known. Our objectives were to determine whether phosphodiesterase-5 is prese...

Justificativa e Objetivos A anestesia da paciente grávida engloba situações diversas e que devem ser analisadas com muita propriedade. Além da exposição do feto e de uma possível ação tóxica dos agentes a serem utilizados na anestesia, devem ser considerados o período gestacional, as características de cada droga e as doses a serem utilizadas. A falta de informações adequadas sobre o risco do u...

Feto-placental infections represent a major cause of pregnancy complications, and yet the underlying molecular and cellular mechanisms of vertical transmission are poorly understood. Listeria monocytogenes, a facultative intracellular pathogen, is one of a group of pathogens that are known to cause feto-placental infections in humans and other mammals. The purpose of this study was to evaluate ...

Experimental evidence indicates that the primary maternal environmental factor that regulates feto-placental growth is substrate delivery to the placental site, which is the product of maternal substrate levels and the rate of placental-bed blood flow. Thus, maternal factors which change either substrate level or flow alter feto-placental growth rate. The best-studied substrate in human pregnan...

To evaluate and analyze the effect of foetal endocsopic tracheal occlusion (FETO) therapy on survival rates of neonatal with congenital diaphragmatic hernia and maternal complications. We performed a systemic review and meta-analysis of three randomized controlled trials (RCTs). The combined data on neonatal survival rates, length of gestational age and rates of premature rupture of membrane fr...

From an evolutionary point of view, an overriding biological priority is to ensure offspring survival. Oxygen is essential for the growing fetus, and during pregnancy the fetus has an increasing demand for oxygen. If the oxygen supply to the fetus is threatened, it is likely that compensatory mechanisms are activated. Impaired development of the placenta in early pregnancy is assumed to be the ...