conclusions the present investigation supports the use of the methanolic extract of a. maurorum as an antiviral drug in folk and modern medicine. this activity may justify its use as a source of natural compounds to control fmdv in infected animals. background foot and mouth disease (fmd) is an infectious disease of cloven-hoofed animals that has adverse economic impacts. given the prevalence o...

since, the most susceptible laboratory animal to foot–and–mouth disease virus (fmdv) is guinea pig, and then one milliliter of fmdv type (o) concentrations of 106-106.5 tcid50was inoculated intradermally (id) to 10 plantar surface of guinea pig (right side). guinea pig adapted virus has been prepared after generalization phase, and then one milliliter of virus was inoculated intradermally to 30...

foot-and-mouth disease is an important viral disease of cloven-hoofed animals. inactivated whole particle virus vaccines are still widely used in prophylactic vaccination campaigns. the choice of adjuvant is a very important factor in enhancing immune responses and the efficacy of inactivated vaccines. montanide isa 61 vg is a new ready-to-use mineral oil-based adjuvant developed by seppic inc....

Little attention has been paid to the aspects of cardiac injury-related foot and mouth disease (FMD) in young animals. So, this research was conducted to evaluate the serum biomarkers and electrocardiographic (ECG) evidence of myocardial injury in the infected lambs with FMD. During an outbreak, 33 lambs with FMD and 11 healthy lambs were randomly enrolled. After blood sampling, ECGs were taken...

Foot-and-mouth disease (FMD) is a contagious viral disease of livestock with significant economic effect. It is prevalent in various regions of Asia, Africa, and South America. The causative agent of this disease is called foot-and-mouth disease virus (FMDV), which is a member of Aphthovirus genus. Vaccination is an effective technique to prevent the complications of FMD and to eradicate the di...

The complete genome sequences of four foot-and-mouth disease viruses of South African territories 1 (SAT 1) serotype are reported. These viruses originate from an outbreak in Nigeria in 2015 and belong to the novel SAT 1 topotype X from the west and central African virus pool.

BACKGROUND Hand, foot and mouth disease (HFMD) has circulated in China and caused yearly outbreak. To understand the transmission of the disease and to assess the spatial variation in cases reported, we examined age-specific transmission characteristics and reporting rates of HFMD for 31 provinces in mainland China. METHODS We first analyzed incidence spatial patterns and age-specific inciden...

BACKGROUND Hand, foot and mouth disease (HFMD) was listed as a notifiable communicable disease in 2008 and is an emerging public health problem in China, especially for children. However, few data are available on the risk assessment of the potential reasons for HFMD in Beijing. This study examined the association of temperature with the incidence of children's HFMD in Beijing at the daily scal...

Several foot-and-mouth disease virus (FMDV) carrier cattle were identified in Vietnam by the recovery of infectious virus from oropharyngeal fluid. This report contains the first near-complete genome sequences of seven viruses from sequential samples from one carrier animal collected over the course of 1 year. The characterization of within-host viral evolution has implications for FMDV control...