j-Ieart size was measured radiographically before and after single or double homograft valve replacement in 69 consecutive patients. Thirty patients had aortic valve replacement, 25 mitral, and 14 both aortic and mitral valve replacement. For aortic valve replacement a fresh unsupported homograft was inserted in the subcoronary position, while for mitral valve replacement afresh semilunar homog...

OBJECTIVE In an effort to make available homografts preserved in a simpler and less costly way, we evaluated the polyethyleneglycol, L-Hydro (LH) method, that consists in the controlled extraction of antigenic substances and the incorporation of anti-inflammatory and anti-thrombotic agent. METHODS We substituted the pulmonary trunk in ten ovines, seven received LH treated pulmonary homografts...

j-Ieart size was measured radiographically before and after single or double homograft valve replacement in 69 consecutive patients. Thirty patients had aortic valve replacement, 25 mitral, and 14 both aortic and mitral valve replacement. For aortic valve replacement a fresh unsupported homograft was inserted in the subcoronary position, while for mitral valve replacement afresh semilunar homog...

Prosthetic replacement of valves in children is limited by size constraints of the prosthesis and lack of growth potential. In specific situations like infective endocarditis, valve preservation is near impossible and in such instances alternatives are hard to get. Furthermore, in the tricuspid position the long-term results of both mechanical and bioprosthesis are not optimal. We used an innov...

Since the first cardiac valve replacement in the early sixth decade of the last century, the search continued for ideal cardiac valve substitute with proven structural durability over a period of 10 to 20 years, central flow orifice without transvalvular gradient, absence of host reactivity deleterious to valve function, non-thrombogenecity without the use of anti-coagulant, resistance to infec...

Cases of massive purulent infection of vascular prosthesis are demonstrated in this study. Infected prosthesis was substituted by arterial homograft, harvested during multi-organ procurement, and stored by the cold ischaemia method. In the follow-up period, the patients were divided into two groups, those treated with immunosuppression (n = 16) and those treated without immunosuppressive drugs ...