from may 1994 to december 1996 thirty patients received viable fresh aortic homografts. mean age was 55 years (13 to 70), male to female ratio was 2/1, 24 operations were elective whereas 6 were semiurgent. predominant lesions were aortic stenosis or regurgitation in lb patients, aortic valve endocarditis in 10, prosthetic valve dysfunction in 3, and aortic root pathology in one patient. from t...

Background. Homograft valves are subject to calcification and structural degeneration in the long term. Blood group matching is performed in many centers, and it remains controversial whether immunologic responses associated with potential blood group incompatibility contribute to the degeneration of unmatched homografts. We studied the expression of carbohydrate blood group antigens on valve e...

BACKGROUND Homograft valves are subject to calcification and structural degeneration in the long term. Blood group matching is performed in many centers, and it remains controversial whether immunologic responses associated with potential blood group incompatibility contribute to the degeneration of unmatched homografts. We studied the expression of carbohydrate blood group antigens on valve en...

The present study was undertaken to measure and compare the viability of the mitral leaflet, chordae, and papillary muscle. The viability of the valves was assessed by autoradiography at regular intervals after sterilization and preservation in antibiotics and nutrient medium. The results showed different rates of decline in viability of the leaflet, muscle, and chordae of the mitral valves. Sl...

Debate continues regarding the long-term clinical and hemodynamic benefit of homograft replacement of the diseased mitral valve. The results of valve replacement with mitral homografts in the 120 patients who have had operation at the Stanford Medical Center from May 1967 to November 1970 are given. The operative mortality rate has been 5% and the late mortality rate 6%. Anticoagulants were sto...

Since I introduced the homograft transplantation en bloc in 1959, more than 2,400 patients with chronic middle-ear inflammation and the conditions resulting from an old radical operation have been operated upon. Different kinds of chemical solution for the conservation of the homograft have been used, and experience has shown that the best solution is a combination of Cialit 1:5,000 and formald...