Background: The Heat shock proteins are stress induced and there is increased evidence of presence of these chaperons extracellular which is considered to be intracellular. Their present cytokine like effect and help in immune recognition, thus indicate strong extracellular action of heat shock protein 70 in maintaining integrity of oral cavity. Hypothesis: The aim of this study was to evaluate...

background permanent antigenic variation of influenza viruses causes a major concern to develop an effective human influenza vaccine. conserved antigens are new vaccine candidates because it is not necessary to match the prepared vaccine with circulating strains. ion channel m2 protein is conserved among all influenza a viruses, allowing the virus to enter host cells. objectives to prepare an e...

Alzheimer's disease (AD) is the most common neurodegenerative disease that caused dementia which has no effective treatment. Growing evidence has demonstrated that AD is a "protein misfolding disorder" that exhibits common features of misfolded, aggregation-prone proteins and selective cell loss in the mature nervous system. Heat shock protein 70 (HSP70) attracts extensive attention worldwide, ...

bacterial and viral triggers are suspected agents in the initial etiology of autoimmune diseases. there are some studies on the etiology of autoimmune disorders which have focused on streptococcal infection and a possible relation with microbial heat shock proteins (hsp) which show significant homology with human heat shock proteins. in addition, some serotypes of streptococci cross-react with ...