seroresponse to the full three - dose of the hepatitis b vaccine (engcrix-b) was studied in 138 medical and paramedical staff from tehran. the vaccine was found to be highly immunogenic. seroconversion rales, scroprotecthn rates and geometric mean titer were found to be 98.$%, 90% and 902.$ mlu/ml, respectively. tills is the first report of sero-rcsponse in normal iranian subjects to the hepati...

conclusions the study results indicated that the neonatal hbv immunization induced a long-term protection against hbv and was very efficacious in reducing chronic hbv infection rate in vaccinated young adults in iran. results anti-hbs seropositivity rate was detected in 224 of 510 [95% ci: 39-47] young adults. breakthrough infection (positive sera for anti-hbc without chronic infection) was obs...

hepatitis b virus (hbv) infection and its sequelae such as cirrhosis and hepatocellular carcinoma has remained a serious public health problem throughout the world. the who strategy for effective control of hbv infection and its complications is mass vaccination of neonates and children within the framework of expanded programme on immunization (epi). vaccination with hepatitis b surface antige...

background: conventional hepatitis b virus (hbv) vaccination fails to achieve efficient protection in about 5–10% of the world population. hence, different strategies have been adopted to ameliorate hbv antibody titers. this study aimed to evaluate the concurrent application of tetanus‑diphtheria (td) and hbv vaccination on hepatitis b surface (hbs) antibody titer in low‑responder healthy indiv...

OBJECTIVE To evaluate the effects of hepatitis B vaccine and immunoglobulin in newborn infants of mothers positive for hepatitis B surface antigen. DESIGN Systematic review and meta-analysis of randomised clinical trials. DATA SOURCES Electronic databases and hand searches. REVIEW METHODS Randomised clinical trials were assessed for methodological quality. Meta-analysis was undertaken on ...

in order to determine the efficacy of recombinant hepatitis b vaccine in iranian infants, we analyzed the efficacy of a recombinant hepatitis b vaccine in 115 infants aged 12-24 months born to hbsag negative mothers who received three doses of hbv antibody to hepatitis b surface antigen (anti-hbs) was checked after the third dose of the vaccine, 94.8% of the infants had developed protective ant...

Background Infants of diabetic mothers (IDMs) have significantly greater risk for spontaneous abortion, stillbirth, congenital malformations and perinatal mortality and morbidity but whether maternal DM affects the neonatal innate immune system is unknown. We aimed to assess the immune response of infants of diabetic mothers (IDMs) with non-gestational DM for Hepatitis B vaccine and to compare ...