OBJECTIVE Ziprasidone is an atypical antipsychotic drug that shows a higher affinity for serotonin 5-HT(2) receptors compared with dopamine D(2) receptors in vitro. The affinity of ziprasidone for these receptors in vivo in patients was examined in a positron emission tomography (PET) study. METHOD The authors conducted a PET study to evaluate D(2) occupancy (using [(11)C]raclopride) and 5-HT...

exceeded losses of nonstructural components from structural ones in most demolished buildings in previous earthquakes and its limitation on functionality of critical facilities and building serviceability after earthquakes should be got the point of view for accounting loss of building as a merit for building performance. this paper attempts to demonstrate the significant role of distribution p...

Background Increasing demand for limited healthcare resources raises questions about appropriate use of inpatient beds. In the first paediatric bed utilisation study at a regional university centre in Ireland, we conducted a cross-sectional study to audit the utilisation of inpatient beds at the Regional Paediatric Unit (RPU) in University Hospital Limerick (UHL), Limerick, Ireland and also exa...

background increasing demand for limited healthcare resources raises questions about appropriate use of inpatient beds. in the first paediatric bed utilisation study at a regional university centre in ireland, we conducted a cross-sectional study to audit the utilisation of inpatient beds at the regional paediatric unit (rpu) in university hospital limerick (uhl), limerick, ireland and also exa...

The performance gap is a measure of the difference between design assumptions and actual in field data. Estimating terms, specifically the operational hours of use, when making such design assumptions in order to predict the impact of lighting upgrades can potentially result in either an overestimate or underestimate of the savings to be made. In this paper, the background of performance gap me...

Objectives: The authors investigated whether models using time series methods can generate accurate short-term forecasts of emergency department (ED) bed occupancy, using traditional historical averages models as comparison. Methods: From July 2005 through June 2006, retrospective hourly ED bed occupancy values were collected from three tertiary care hospitals. Three models of ED bed occupancy ...

Occupancy profile is one of the driving factors behind discrepancies between the measured and simulated energy consumption of buildings. The frequencies of occupants leaving their offices and the corresponding durations of absences have significant impact on energy use and the operational controls of buildings. This study used statistical methods to analyze the occupancy status, based on measur...

This article (a follow on from an article concentrating on Northern Ireland) examines the relationship between percentage bed occupancy (PO), turnover interval (TI) and methicillin-resistant Staphylococcus aureus (MRSA) rates in the acute beds of specialist English hospital trusts and describes the TI and levels of bed occupancy. The data were collected from publicly available data: MRSA rates ...