The hub-and-spoke network (HSN) design generally assumes direct transportation between a spoke node and its assigned hub, while the spoke’s demand may be far less than truckload. Therefore, total number of trucks on increases unnecessarily. We form drone-based traveling salesman problem (TSP-D) for cluster spokes to hub. A truck starts from visiting each hub in turn finally returning propose th...

Hub-and-Spoke Free Trade Areas* This paper analyzes how the sequential formation of free trade areas affects the volume of trade between member countries. In a three--country, three-good model, if two countries have a free trade area, and both sign a similar agreement with the third, trade between the two decreases, and welfare rises in both. However, if only one of them signs an FTA with the t...

Telemedicine (also known as telehealth) is a means to increase access to care, one of the foundations of the Triple Aim. However, the expansion of telemedicine services in the United States has been relatively slow. We previously examined the extent of uptake of hospital based telemedicine using the 2013 HIMSS (Healthcare Information and Management Systems Society) Analytics national database o...

BACKGROUND AND PURPOSE The American Stroke Association guidelines emphasized the need for further high-quality studies that assess agreement by radiologists and nonradiologists engaged in emergency telestroke assessments and decision-making. Therefore, the objective of this study was to determine the level of agreement of baseline brain CT scan interpretations of patients with acute stroke pres...

Transportation networks frequently employ hub-and-spoke network architectures to route flows between many origin and destination pairs. In this paper, we deal with a problem, called the single allocation hub-and-spoke network design problem. In the single allocation hub-andspoke network design problem, the goal is to allocate each non-hub node to exactly one of given hub nodes so as to minimize...

Airline networks may be interpreted as structures that express strategic choices made by airlines to serve or not to serve given airports. Research into network strategies of airlines in the past has focused on economies (of density) and market power. More recent research focuses on managerial decisions related to capacity choices, such as the frequency or scheduling of flights, which are relat...

— We use panel data consisting of 96 countries and covering the period 1960–2000 to investigate the effects of free trade agreements (FTAs) and hub-and-spoke systems of FTA on exports. Our empirical results imply an annual growth rate of 5.57% in exports and hence a doubling of exports after 12.4 years between FTA partners. Non-overlapping FTAs account for 4.12%, while hub-andspoke FTAs account...