Introduction: Laryngeal cancer is the second most common cancer involving the respiratory tract, second only to lung cancer. Previous studies have shown opium dependency to be a possible risk factor for laryngeal cancer. Opium consumption is a major problem in some parts of the world. The aim of this study was to investigate the effect of opium consumption on the pattern of involvement in laryn...

following the first report of laryngeal small cell carcinoma in canada in 1972,only 82 cases of this cancer has been reported in the literature untill 2001.this cancer originates from laryngeal neuroendocrine cells.It,s clinical presentation consists of hoarseness,breathing difficulty:and cigarette smoking is the most important risk factor.this type of cancer is mostly presented after 50 years ...

The aim of this study is to determine whether there is a role of podoplanin and glutathione S-transferases T1 (GST-T1) expression in laryngeal squamous cell carcinoma. The study was completed with 33 patients and gene expression analysis was performed by qRT–PCR. The podoplanin and GST-T1 expression patterns were analyzed to determine their correlation with clinicopathologic parameters of lar...

the aim of this study is to determine whether there is a role of podoplanin and glutathione s-transferases t1 (gst-t1) expression in laryngeal squamous cell carcinoma. the study was completed with 33 patients and gene expression analysis was performed by qrt–pcr. the podoplanin and gst-t1 expression patterns were analyzed to determine their correlation with clinicopathologic parameters of laryn...

BACKGROUND MicroRNA (miRNA) is an emerging subclass of small non-coding RNAs that regulates gene expression and has a pivotal role for many physiological processes including cancer development. Recent reports revealed the role of miRNAs as ideal biomarkers and therapeutic targets due to their tissue- or disease-specific nature. Head and neck cancer (HNC) is a major cause of cancer-related morta...

intra-operative management of thyroid gland in laryngeal cancer is controversial. to determine the rate of thyroid involvement in patients with laryngeal cancer treated by radical surgical excision, we reviewed the records during 1996-2000 in imam khomeini hospital, cancer institute, and amir alam hospital.we studied several factors such as age, gender, and tumor location, presence of thyroid i...

Introduction: Actinomycosis is a systemic chronic bacterial infection caused by Actinomyces Israelii, an anaerobic organism normally resident in the human mouth. However, the actinomycosis of the larynx is very rare, and only about 15 cases have been reported in the literature so far. Most of the cases reported occurred in patients who had previously undergone radiotherapy for laryngeal cancer...

introduction: actinomycosis is a systemic chronic bacterial infection caused by actinomyces israelii, an anaerobic organism normally resident in the human mouth. however, the actinomycosis of the larynx is very rare, and only about 15 cases have been reported in the literature so far. most of the cases reported occurred in patients who had previously undergone radiotherapy for laryngeal cancer....

Carbon dioxide (CO2) laser surgery as a conservative tool plays a peculiar role in the management of head and neck cancer. Numerous patients who were candidates for transoral laryngeal microsurgery have forced us to eliminate frozen-section evaluation of surgical margins and use a magnified view of the larynx. The present study evaluated surgeon-judged negative margins with permanent microscopi...