the purpose of this study was to investigate and compare whether the explant supernatants prepared from endometrial tissues during the proliferative phase, secretory phase and early pregnancy differ in immunosuppressive activity. specimens of nonpregnant endometrium from hysterectomies and normal first trimester decidua following elective aspiration termination of pregnancy were obtained. super...

The purpose of this study was to investigate and compare whether the explant supernatants prepared from endometrial tissues during the proliferative phase, secretory phase and early pregnancy differ in immunosuppressive activity. Specimens of nonpregnant endometrium from hysterectomies and normal first trimester decidua following elective aspiration termination of pregnancy were obtained. ...

Semenogelin (Sg) is secreted from the seminal vesicle and constitutes a major gel-forming protein in semen. Sg plays an important role for inhibiting sperm motility. Human seminal plasma has immunosuppressive effects on human peripheral blood lymphocytes (PBL). Here, we studied whether human Sg exerted immunosuppressive effects on human lymphocyte functions in vitro. We found that Sg reduced pr...

background: the expanse of dendritic cells (dc) differentiation plays an important role in determining immune response. dc-based immunosuppressive drugs have notable side effects in increasing the risk of infectious diseases and cancers. g2013, as a novel anti-inflammatory and immunosuppressive agent, has been tested in experimental model of multiple sclerosis. the aim of this study was to cond...

The use of immunosuppressive therapy for inflammatory cardiomyopathy is controversial. The aim of this review is to summarize the current empirical evidence for immunosuppressive treatment in inflammatory cardiomyopathy. We conducted a meta-analysis of all randomized controlled trials (RCTs) that compared immunosuppressive therapy with either placebo or conventional treatment in patients with i...

introduction and aims: impact of treatment on progression of fibrosis in autoimmune hepatitis (aih) is unknown. we assessed the changes in liver fibrosis before and after treatment among these patients. materials and methods: nineteen aih patients who had paired liver biopsies were studied. of these, seven had been treated with 6 months of cyclosporine-a and the rest with 6 months of prednisolo...