abstract   background: the polymorphic variants at codon 72 of the p53 gene, encoding either proline or arginine at residue 72, produce marked change in the structure of p53. from the evidence that the dnamismatch repair system and p53 interact to maintain genomic integrity, we hypothesized that the codon 72 variation may influence the prevalence of microsatellite instability a feature of malig...

  Background and Objectives: Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal dominant cancer predisposition syndrome caused by germ-line mutations in DNA mismatch repair genes. Tumors arising as a result of these mutations display instability in a sequence area known as microsatellites. Studies have shown that some Bethesda markers (BAT25, BAT26) are more efficient than other...

the accuracy and efficiency of the elements proposed by finite element method (fem) considerably depend on the interpolating functions namely shape functions used to formulate the displacement field within the element. in the present study, novel functions, namely basic displacements functions (bdfs), are introduced and exploited for structural analysis of nanobeams using finite element method ...

Asymptotically exact and nonlocal third order nonlinear evolution equations are derivedfor two counterpropagating surface capillary gravity wave packets in deep water in thepresence of wind flowing over water.From these evolution equations stability analysis ismade for a uniform standing surface capillary gravity wave trains for longitudinal perturbation. Instability condition is obtained and g...

Purpose: Many research studies reported balance disorder as one of the most important consequences of Functional Ankle Instability. However, the Balance Recovery Strategy, which its deficiency can cause poor balance or secondary damages, has not been investigated in previous studies yet. The purpose of this article is to study the Balance Recovery Strategy in athletes with Functional Ankle Inst...