ISIS är ett centrum med nio industripartners och sex forskningsgrupper, med inriktning mot industriella styroch övervakningsproblem, och med syfte att använda och utveckla verktyg b̊ade fr̊an datavetenskap och reglerteknik. De största utmaningarna för ett kompetenscentrum är att h̊alla en bra balans mellan vetenskaplig production och industriellt relevans, att producera välutbildade personer och a...

BACKGROUND Because treatment of metastatic colon cancer is noncurative, new treatments are needed. This trial evaluated the antitumor effects of two targeted anticancer agents: (a) ISIS 3521, an antisense inhibitor of the protein kinase C alpha; and (b) ISIS 5132, an antisense inhibitor of c-raf kinase in patients untreated previously with recurrent or metastatic colorectal carcinoma. PATIENT...

PURPOSE Protein kinase C (PKC)-alpha and Raf-1 are important elements of proliferative signal transduction pathways in both normal and malignant cells. Abrogation of either Raf-1 or PKC-alpha function can both inhibit cellular proliferation and induce apoptosis in several experimental cancer models including prostate cancer cell lines. ISIS 3521 and ISIS 5132 are antisense phosphorothioate olig...

Team ISIS (ISI Synthetic) successfully participated in the rst international RoboCup soccer tournament (RoboCup'97) held in Nagoya, Japan, in August 1997. ISIS won the third-place prize in over 30 teams that participated in the simulation league of RoboCup'97 (the most popular among the three RoboCup'97 leagues). In terms of research accomplishments, ISIS illustrated the usefulness of an explic...

BACKGROUND Localizing the human interhemispheric region is of interest in image analysis mainly because it can be used for hemisphere separation and as a preprocessing step for interhemispheric structure localization. Many existing methods focus on only one of these applications. NEW METHOD Here a new Intensity and Symmetry based Interhemispheric Surface extraction method (ISIS) that enables ...

From its start, the so-called Islamic State of Iraq and the Levant (ISIL/ISIS) has been successfully exploiting social media networks, most notoriously Twitter, to promote its propaganda and recruit new members, resulting in thousands of social media users adopting a pro-ISIS stance every year. Automatic identification of pro-ISIS users on social media has, thus, become the centre of interest f...

The disposition of ISIS 2922, a phosphorothioate oligonucleotide for treatment of cytomegalovirus associated retinitis, was evaluated in rabbits. Vitreous humor and retina samples were collected from rabbits that received a single intravitreal injection of 66 microg [14C]-labeled ISIS 2922 and were analyzed using anion exchange HPLC. Four hr postdosing, the concentration of ISIS 2922 in vitreou...

Terrorist groups like the Islamic State of Iraq and Syria (ISIS) have exploited social media such as Twitter to spread their propaganda and to recruit new members. In this work we study the extent to which ISIS is able to spread their message beyond their immediate supporters. Are they operating in their own sphere with limited interaction with the overall community? Or are they well rooted amo...