نتایج جستجو برای: isis

تعداد نتایج: 2014  

باقری, سامیه, کوهکن, علیرضا,

Since the emergence in Levant, including Iraq and Syria, ISIS Takfiri– Terrorist Group has claimed Khorasan Province (Afghanistan& some regions in central Asia) as part of its reign and by the way proclaimed its existence and identity under this title. The first issue about the presence of ISIS In Khorasan Province, especially in those of central Asia which this research focuses on, is that wha...

Journal: :American Journal of Islam and Society 2018

Journal: :Arena Hukum 2023

The repatriation of ex-ISIS members to Indonesia will have an impact on the community, because previous jihadi alumni from Afghanistan carried out terrorist bombings in several locations after they returned Indonesia. This research analyze classification Indonesian citizens who had joined ISIS; ISIS according regulations and reformulation ISIS. normative juridical uses statutory approach concep...

Journal: :Investigative ophthalmology & visual science 2001
S P Henry R C Miner W L Drew J Fitchett C York-Defalco L M Rapp A A Levin

PURPOSE To compare the antiviral activity and ocular distribution of first- and second-generation antisense oligonucleotides intended for the treatment of cytomegalovirus (CMV) retinitis. METHODS The antiviral activity of ISIS 13312 and ISIS 2922 (Isis Pharmaceuticals, Inc., Carlsbad, CA) against 10 clinical CMV isolates was compared with a plaque-reduction assay. The ocular pharmacokinetics ...

2016
Rosie Z Yu Mark J Graham Noah Post Stan Riney Thomas Zanardi Shannon Hall Jennifer Burkey Colby S Shemesh Thazha P Prakash Punit P Seth Eric E Swayze Richard S Geary Yanfeng Wang Scott Henry

Triantennary N-acetyl galactosamine (GalNAc3)-conjugated antisense oligonucleotides (ASOs) have greatly improved potency via receptor-mediated uptake. In the present study, the in vivo pharmacology of a 2'-O-(2-methoxyethyl)-modified ASO conjugated with GalNAc3 (ISIS 681257) together with its unmodified congener (ISIS 494372) targeting human apolipoprotein (a) (apo(a)), were studied in human LP...

Journal: :Nucleic acids research 2000
M K Bijsterbosch E T Rump R L De Vrueh R Dorland R van Veghel K L Tivel E A Biessen T J van Berkel M Manoharan

Several studies have shown improved efficacy of cholesteryl-conjugated phosphorothioate antisense oligodeoxynucleotides. To gain insight into the mechanisms of the improved efficacy in vivo, we investigated the disposition of ISIS-9388, the 3'-cholesterol analog of the ICAM-1-specific phosphorothioate oligodeoxynucleotide ISIS-3082, in rats. Intravenously injected [(3)H]ISIS-9388 was cleared fr...

2016
Chanchal Kumar

The foundations of the ISIS were formed following the US-led invasion of Iraq (2003). The ISIS or the ISIL was formed by the insurgents of the Tanzim Qaidat al-Jihad fi Bilad al-Rafidayn, also known as the al-Qaeda in Iraq (aQI). This group has been given the title of “terrorist organization” by the United Nations, European Union, the United States, Saudi Arabia, and many others. ISIS now contr...

2016
Matthew Rowe Hassan Saif

The emergence and actions of the so-called Islamic State of Iraq and the Levant (ISIL/ISIS) has received widespread news coverage across the World, largely due to their capture of large swathes of land across Syria and Iraq, and the publishing of execution and propaganda videos. Enticed by such material published on social media and attracted to the cause of ISIS, there have been numerous repor...

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