Wilhelm Pfeffer [3] published his book Osmotische Untersuchungen: Studien Zur Zellmechanik (Osmotic Investigations: Studies on Cell Mechanics) in 1877 during his time as a professor of botany at the University of Basel [4] in Basel, Switzerland. Gordon R. Kepner and Eduard J. Stadelmann translated the book into English in 1985. Verlag von Wilhelm Engelmann in Leipzig [5], Germany, published the...

The classic rank-based method for comparing J dependent groups is Friedman’s test. Consider a random sample of n vectors from some J-variate distribution. As is well-known, Friedman’s test assigns ranks to the values within each vector and is based on a compound symmetry assumption under the hypothesis of no treatment effect (e.g., Brunner, Domhof, & Langer, p. 68). That is, the distribution is...

Schmitt H (1977) The pharmacology of clonidine and related products. In Handbuch der experimentellen Pharmakologie, edited by F Gross, Springer-Verlag, Berlin-Heidleberg-New York, 39: pp. 299-396 Sigg EB, Keim KL, Kepner K (1971) Selective effect of diazepam on certain central sympathetic centers. Neuropharmacology 10: 621-629 Snider RS, Niemer WT (1961) A Stereotaxic Atlas of the Cat Brain. Ch...

The carrier-within-a-carrier (CWC)dor “airline-within-an-airline” (AWA)dapproach has become an integral part of many airlines' marketing strategies in the AsiaePacific region where several full-service national airlines operate low-cost/low-fare subsidiary airlines. The CWC approach is a response to competition from low-cost carriers based on product differentiation, i.e., a ‘two brands’ busine...

HE PURPOSE OF THIS PAPER 5 to describe a micromethod for the fluorometric determination of calcium in blood serum, plasma, urine, and cerebrospinal fluid. The method is an adaptation of the fluorometric procedure of Wallach et al (1, 2) and Kepner and Hercules (3) to the TJnopette system* (4, s). The original procedure involved the preparation of a stock solution of Calcein or fluorescein compl...

Calcium has been determined fluorometrically in serum with use of calcein (fluorescein-methylene-iminodiacetic acid, C30H26N203) throughout the last decade. Wallach et al. (1, 2) developed the first useable method in 1959, which was later modified by Kepner and Hercules (3) in 1963, Phillips (4) in 1964, and Hill (5) in 1965. Moser and Gerarde (6) adapted the method to the “trNOPETTE”1 System i...