BACKGROUND Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder, which may result from alteration of the gastrointestinal microbiota following gastrointestinal infection, or with intestinal dysbiosis or small intestinal bacterial overgrowth. This may be treated with antibiotics, but there is concern that widespread antibiotic use might lead to antibiotic resistance. S...

In this work enzyme-assisted extraction (EAE) and pressurized liquid extraction (PLE) are applied for extraction of natural compounds from lemon balm (Melissa officinalis). Cellulase, endo-β-1,4 xylanase and pectinase were studied in order to degrade cell wall of lemon balm leaves and to release phenolic compounds. On the other hand, in order to compare the performance obtained with EAE, PLE us...

Over the last decades polyetiological metabolic diseases such as obesity and type 2 diabetes have emerged as a global epidemic. Efficient strategies for prevention and treatment include dietary intervention and the development of validated nutraceuticals. Safe extracts of edible plants provide a resource of structurally diverse molecules that can effectively interfere with multifactorial diseas...

effect of adding melissa officinalis aqueous extract was studied on immune response and performance in 200 ross 308 broiler chicks in a completely randomized design with five treatments and four replicates and 10 observations per replicate. the amounts of 0 (control), 0.5, 1, 1.5 and 2 ml/l lemon balm extract were added in drinking water for 42 days. humoral immunity was evaluated by injection ...

objectives the present study aimed to determine the effects of lemon balm alone and in combination with nepeta menthoides on menstrual bleeding in students with premenstrual syndrome. patients and methods this triple-blind randomized controlled trial included 93 female students with aged 18 years and older. the intervention groups received 500 mg capsules of lemon balm alone or lemon balm in co...

in this research, effect of vermicompost and plant growth promoting rhizobacteria (pgpr) on physiological traits of lemon balm under drought stress condition was investigated in year 2012 at karaj research institute of forest and rangelands. experiment was conducted as split-split plot in a randomized complete block design with three replications. irrigation (normal: irrigated to field capacity...

BACKGROUND As the use of herbal supplements continues to rise throughout the world, the potential for drug-herbal interactions also increases. For chemotherapeutic prodrugs, this interaction could prevent the metabolic conversion of the prodrug to its active metabolite(s), thereby potentially resulting in subtherapeutic systemic exposure of the drug and reduced efficacy of the therapy. METHOD...

Oxidative processes, especially lipid peroxidation (LPO), are assumed to increase during ageing. In an attempt to provide experimental evidence for this assumption lemon balm plants (Melissa officinalis L.) of different age and location were analyzed for oxidatively caused changes in the etheric oil composition. The investigation revealed that the caryophyl­ lene oxide (CarO) content of lemon b...

In the current study, we screened 7 clonal lines from single seed phenotypes of Lamiaceae family for the inhibition of alpha-amylase, alpha-glucosidase and angiotensin converting enzyme (ACE) inhibitory activity. Water extracts of oregano had the highest alpha-glucosidase inhibition activity (93.7%), followed by chocolate mint (85.9%) and lemon balm (83.9%). Sage (78.4 %), and three different c...