background: metabolic derangements in type 2 diabetes mellitus (t2dm) are likely to affect skeletal muscle contractile functions adversely. levo-carnitine improves muscle contractile functions in healthy humans and rats and corrects metabolic derangements in t2dm. therefore, it is likely to improve muscle contractile functions in t2dm as well. this study was designed to determine the effect of ...

The levo-transposed aorta has previously been considered diagnostic of corrected transposition of the great arteries and hence ventricular inversion in situs solitus. Increasing experience with conotruncal abnormalities has shown that an abnormally leftward aorta may be found in patients with normally related ventricles (D-ventricular loop) and hemodynamically complete transposition of the grea...

Aortocaval fistula (ACF)-induced volume overload (VO) heart failure (HF) results in progressive left ventricular (LV) dysfunction. Hemodynamic load reversal during pre-HF (4 wk post-ACF; REV) results in rapid structural but delayed functional recovery. This study investigated myocyte and myofilament function in ACF and REV and tested the hypothesis that a myofilament Ca(2+) sensitizer would imp...

1. The tripeptide glycyl-levo-alanyl-glycine in solution of either one or ten equivalents of alkali does not undergo racemization on standing. 2. The dipeptide levo-alanyl-glycine under the conditions given in (1) does not undergo racemization. 3. In ketopiperazines, levo-alanyl-glycine anhydride and in levo-prolyl-glycine anhydride under the influence of dilute alkalies, racemization takes pla...

OBJECTIVE To compare the effects of combined and individual supplementation of cholecalciferol and levo carnitine on plasma glucose, plasma insulin and insulin resistance in type 2 diabetic rats. METHODS The randomised controlled trial was conducted at the Department of Physiology, Army Medical College, Rawalpindi, between October 2010 and April 2011. It comprised 80 healthy Sprague Dawley ra...

Background: To determine the effect of combined supplementation of pioglitazone and levo carnitine on plasma glucose, insulin resistance and serum adiponectin in T2DM mice. Methods: In this randomized controlled trial 40 healthy BALB/c mice were divided into four groups (n=10 each). Mice were fed high fat diet for two weeks followed by intraperitoneal injection of streptozotocin to induce T2DM....

— High-performance computer processors have become much more complex in recent years, especially in the research community. We describe a Web-based interactive simulation and graphics tool under development at URI for the new Levo research processor. The tool mimics Levo operation and structure, aiding in broad understanding by researchers, students and engineers. Index Terms— Microarchitecture...

Development and selection of an ideal scaffold is of importance for tissue engineering. Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) is a biocompatible bioresorbable copolymer that belongs to the polyhydroxyalkanoate family. Because of its good biocompatibility, PHBHHx has been widely used as a cell scaffold for tissue engineering. This review focuses on the utilization of PHBHHx-base...

STUDY OBJECTIVE To determine the steady-state, extracellular, and intracellular pulmonary disposition of moxifloxacin (MXF), levofloxacin (LEVO), and azithromycin (AZI) relative to that of the plasma over a 24-h dosing interval. DESIGN Randomized, multicenter, open-label investigation. PATIENTS Forty-seven older adults (mean [+/- SD] age, 62 +/- 13 years) undergoing diagnostic bronchoscopy....

usually centres on improving dopaminergic func tion in the nigro-striatal pathways. Levo-dopa and selegiline increase the amount of synaptic dopamine available; apomorphine, bromocriptlne and pergolide are agonists at dopamine receptors. Symptoms may also be improved by redressing the balance of dopaminergic and cholinergic activity. Benzhexol, procyclidine and orphenadrine, among others, are a...