Perindopril arginine and Indapamide hemihydrate in combination were proven to have a synergistic antihypertensive impact when compared with the use of each component alone. Therefore, a new Ultra-High Performance Liquid Chromatography coupled with Ultraviolet detector (UHPLC-UV) method has been developed and subsequently validated for simultaneous determination of the anti-hypertensive combinat...

Structural and thermal data were obtained for a novel hemihydrate of 6-mercaptopurine. The hemihydrate shows increased solubility and bioavailability when compared to the monohydrate form, better stability against conversion in aqueous media than the anhydrate form, and a dehydration temperature of 240 °C, the highest of any known hydrate crystal.

Gypsum (calcium sulfate dihydrate) is one of the most used inorganic binding materials in world. During calcination, calcium subhydrates are formed and, for technical reasons, mixed with water to form dihydrate again. Therefore, dehydration process gypsum and rehydration hemihydrate were investigated. This technically performed three different ways. Heating up, i.e., a rotary kiln, leads prefer...

The aim of current study was the validation of TLC densitometric method for identification and determination of Estradiol hemihydrate in dosage forms. The TLC conditions were: glass plates with Silicagel G60F254; mobile phase: chloroform : water = 90 : 10 v/v. Linearity accordance between the concentration and spot area in range: 5.10-4 g/ml ÷ 5.10-3 g/ml is proved by the regression equation: y...

The Co centre in the title compound, [Co(C(14)H(11)N(2)O(2))(2)Cl(C(3)H(4)N(2))]·0.5H(2)O, shows a slightly distorted octa-hedral coordination geometry. The glyoximate units of the mol-ecule are linked by O-H⋯O hydrogen bonds with the H atom almost in the middle of the two O atoms. The crystal packing is stabilized through inter-molecular N-H⋯O, N-H⋯N and O-H⋯Cl hydrogen bonds. The uncoordinate...