نتایج جستجو برای: ligustilide essential oil
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چکیده کنه تارتن دو لکه ای tetranychus urticae koch یکی از چندخوارترین آفات شناخته شده محصولات کشاورزی دنیا به حساب می آید. در این بررسی جمعیت تخم و مراحل فعال این کنه در شرایط آلودگی طبیعی و مصنوعی در برگ های 8 رقم لوبیا در سال 1392 در گلخانه و مزرعه تحقیقاتی دانشکده کشاورزی دانشگاه ارومیه موردمطالعه قرار گرفت. آزمایش به صورت طرح کاملاً تصادفی برای شرایط مزرعه در10 تکرار و برای شرایط گلخانه ای...
Heat-shock protein 70 (HSP70) is known to function as a protective molecular chaperone that is massively induced in response to misfolded proteins following cerebral ischemia. The objective of this study was to characterize HSP70 induction by Z-ligustilide and explore its potential role in protection against cerebral ischemia-reperfusion injury. Our results demonstrated that the intranasal admi...
The purpose of the present study was to investigate the effect of ligustilide on vasodilatation in rat mesenteric artery and the mechanisms responsible for it. Isometric tension of rat mesenteric artery rings was recorded by a sensitive myograph system in vitro. The results showed that ligustilide at concentrations more than 10 microM relaxed potassium chloride (KCl)-preconstricted rat mesenter...
Z-ligustilide (LIG), an essential oil extract from Radix Angelica sinensis, has broad pharmaceutical applications in treating cardio-vascular diseases and ischemic brain injury. Recently, LIG has been connected to Glioblastoma multiforme (GBM) because of its structural similarity to 3-n-alkyphthalide (NBP), which is specifically cytotoxic to GBM cells. Hence, we investigated LIG's effect on GBM...
Proliferation and migration of vascular smooth muscle cells (VSMCs) are believed to develop atherosclerosis and venous bypass graft disease. Ligustilide is widely used to treat some pathological settings such as atherosclerosis and hypertension. The aim of this study was to examine the effect of ligustilide on VSMCs proliferation. The results show that ligustilide significantly inhibited VSMCs ...
Ligustilide is the most abundant bioactive ingredient in Rhizoma Chuanxiong, a Chinese medicinal herb commonly used for the treatment of cardiovascular ailments. The present study reported, for the first time, the pharmacokinetics of ligustilide, administered in its pure form and in an herbal extract, in rats. After i.v. administration of pure ligustilide, it was distributed extensively (V(d), ...
پژوهش های بسیاری نشان داده اند که گیاهان جنس zygophyllum غنی از ترکیبات تری ترپن ساپونین وکیونوویک اسید وفلانویید هستند . در این پژوهش به بررسی سه دسته از ترکیبات طبیعی پرداخته شده است یکی از این دسته ترکیبات روغن های فرار به نام essential oil هستند که از این دسته 27 ماده شناسایی شد ومقدار آنها در گیاه مشخص گردید. دومین دسته تر کیبات آنتراسن است که از این دسته نیز 2 ترکیب مشخص گردید وسومین د...
Emerging evidence indicates epigenetic modification represses estrogen receptor α (ERα) and contributes to the resistance to tamoxifen in aggressive ERα-negative (ERα-) breast cancer. Z-ligustilide is a major compound in Radix Angelica sinensis, an herb from traditional Chinese medicine (TCM) most frequently prescribed for breast cancer. However, the role of Z-ligustilide in ERα- breast cancer ...
ability throughout the world. More than 80% of all strokes are a result of cerebral ischemia. Approximately 20% of stroke patients do not survive the first month and less than 30% of those who survive the first six months would become dependent on others. In correlation with the socio-economic importance of ischemic stroke, neuroprotective agents with different modes of action and an extended a...
Danggui Buxue Tang (DBT), a herbal decoction composed of Radix Astragali (RA) and Radix Angelica sinensis (RAS), has been used for treating menopausal irregularity in women for more than 800 years in China. According to the old tradition, RAS had to be processed with yellow wine before DBT preparation, which markedly reduced the amount of ligustilide in RAS and DBT, as well as enhanced the bioa...
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