Toll-like receptors (TLR) triggering of B cells are known to promote B cell expansion, differentiation of B cells into antibody-producing and memory cells, but the TLR responses of porcine B cells is poorly characterized. Therefore, this study investigated the response pattern of porcine B cell subsets to a large collection of TLR ligands and demonstrates that the TLR2 ligand Pam3Cys-SK4 and th...

OBJECTIVE The aim of the study is to describe a group of patients with a highly destructive and asymptomatic form of psoriatic arthritis, mimicking a Charcot-like joint disease. METHODS We studied 180 patients with psoriatic arthritis and identified 4 patients with arthritis mutilans mimicking a Charcot-like joint disease. Clinical history, physical exam, and immunological testing were perfor...

Considering a commutative unital quantale L as the truth value table and using the tool of L-generalized convergence structures of stratified L-filters, this paper introduces a kind of fuzzy upper topology, called fuzzy S-upper topology, on L-preordered sets. It is shown that every fuzzy join-preserving L-subset is open in this topology. When L is a complete Heyting algebra, for every completel...

In this paper, we extend the construction of a fuzzy subgroup generated by a fuzzy subset to $L$-setting. This construction is illustrated by an example. We also prove that for an $L$-subset of a group, the subgroup generated by its level subset is the level subset of the subgroup generated by that $L$-subset provided the given $L$-subset possesses sup-property.