نتایج جستجو برای: like toxin subtypes
تعداد نتایج: 737871 فیلتر نتایج به سال:
When Shiga toxin-producing Escherichia coli (STEC) strains emerged as agents of human disease, two types of toxin were identified: Shiga toxin type 1 (Stx1) (almost identical to Shiga toxin produced by Shigella dysenteriae type 1) and the immunologically distinct type 2 (Stx2). Subsequently, numerous STEC strains have been characterized that express toxins with variations in amino acid sequence...
Botulinum neurotoxins (BoNTs) cause the disease botulism, which can be lethal if untreated. There are seven known serotypes of BoNT, A-G, defined by their response to antisera. Many serotypes are distinguished into differing subtypes based on amino acid sequence, and many subtypes are further differentiated into toxin variants. Previous work in our laboratory described the use of a proteomics a...
Introduction: In this study, the effect of botulinum toxin A and clopidogrel and concomitant administration of them in the survival of random skin flap in rat model were studied. Correspondence: Ghasemali. Khorasani, MD. Surgery Department, Immam Khomeini Hospital Complex, Tehran University of Medical Sciences. ...
Recombinant botulinum Hc (rBoNT Hc) vaccines for serotypes C1 and D were produced in the yeast Pichia pastoris and used to determine protection against four distinct BoNT C and D toxin subtypes. Mice were vaccinated with rBoNT/C1 Hc, rBoNT/D Hc, or with a combination of both vaccines and challenged with BoNT C1, D, C/D, or D/C toxin. Mice receiving monovalent vaccinations were partially or comp...
Bcl-2, a well-known anti-apoptotic gene, promotes cell viability without cell proliferation. Expression of the bcl-2 oncogene is reported in certain low grade neoplasms including Basal Cell Carcinomas(BCCs). Bcl-2 expression in BCCs is contradictory, with 67-100% immunopositivity being reported. The purpose of this study was to evaluate bcl-2 expression in the indolent variants of B...
ABSTRACT: The present study was aimed at subtyping of Stx1 and Stx2 genes characterization antimicrobial resistance in 106 Shiga toxin-producing Escherichia coli (STEC) strains isolated from cattle sheep feces. PCR used to determine the subtypes, disk-diffusion method evaluate resistance. Ten antibiotics five different classes were tested. Among isolates bovine origin, two subtypes (Stx1a Stx1c...
Shiga toxin-producing Escherichia coli (STEC) belonging to certain serogroups (e.g., O157 and O26) can cause serious conditions like hemolytic-uremic syndrome (HUS), but other strains might be equally pathogenic. While virulence factors, like stx and eae, have been well studied, little is known about the prevalence of the E. coli hemolysin genes (hlyA, ehxA, e-hlyA, and sheA) in association wit...
Following the recent outbreak of Shiga toxin-producing Escherichia coli (STEC) O104:H4 infection in Germany, the demand for fast detection of STEC has again increased. Various real-time PCR-based methods enabling detection of Shiga toxin genes (stx) have been developed and can be used for applications in food microbiology. The present study was conducted to evaluate the reliability of seven com...
Objective: To investigate the frequency of paroxysmal nocturnal hemoglobinuria (PNH), an acquired clonal hematopoietic stem cell disease resulting in complement-mediated hemolysis, patients with lymphoma by flow cytometry.Methods: Fifty who were admitted to hematology clinic, newly diagnosed and not yet treated included this study conducted 2014. The presence PNH clones was checked FLAER cytome...
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