background: lung cancer is considered as one of the most frequent cancers worldwide, and has been the cause of more than onemillion mortalities each year. exposure to tobacco smoke is the primary cause of most lung cancers, since it contains several thousandcompounds, including more than 50 known carcinogens. however, a small fraction of individuals who are exposed to tobacco smokedevelop lung ...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : lung cancer has remained the most prevalent malignancy worldwide. it is the fifth leading cause of cancer death in iran. nevertheless, during last few years a gradual permanent increase in its incidence has been reported. although the crucial role of tobacco smoke in lung cancer initiation has long been establ...

background: lung cancer is one of the most fatal and preventable cancers. in this study, we sought to investigate about trend in incidence of lung cancer in kermanshah province -iran. methods: all pathology reports on lung cancer were collected from pathology centers in kermanshah province in recent 11 years (1997-2007). after merging the data with cases reported in, province health centre data...

Circulating microRNAs have been recognized as promising biomarkers for the detection of lung cancer. The objective of this study was to evaluate miR-10b, miR-1 and, miR-30a in the plasma samples of lung cancer patients to confirm any possible relevance in the early detection of lung cancer. Plasma samples from 47 non-small-cell lung cancer patients and 41 cancer-free subjects were evaluated for...

background in the diagnosis of malignant lymph nodes (lns) and staging of lung cancer, sampling of mediastinal and hilar lns is essential. mediastinoscopy is known as the gold standard. convex probe (cp) endobronchial ultrasound (ebus)-guided transbronchial needle aspiration (tbna) is a noninvasive and highly sensitive diagnostic method in mediastinal and hilar ln sampling. objectives evaluatin...

background: cisplatin-based chemotherapy is the standard treatment for advanced non-small cell lung cancer (nsclc). many novel drugs, including gemcitabine, vinorelbine, paclitaxel and docetaxel have been used in combination with cisplatin in this setting. of these drugs, gemcitabine is reported to have a high response rate and acceptable toxicity. the aim of this study was to evaluate the effi...

we describe a patient with newly diagnosed limy cancer. staging was performed with ct and mediastinoscopy. fdg pet scan was performed and confirmed increased metabolic activity in the primary tumor as well as the hilar lymph node. seven months after initial presentation, the patient was found to have two lytic lesions in the pelvis on plain radiograph. hone scan was negative but pet demonstrate...