In the crystal structure of the title compound, C(8)H(12)N(+)·Cl(-), all H atoms bonded to the ammonium N atom are hydrogen bonded to the chloride ions, with N⋯Cl distances in the range 3.080 (2)-3.136 (2) Å, resulting in 16-membered macrocyclic rings involving four formula units of the title compound.

The title compound, C(76)H(80)O(16), is a macrocyclic structure. This novel resorcin[4]arene derivative has (meth-oxy-carbon-yl)meth-oxy 'head' groups on the upper rim. The compound has a C(2v) 'boat' geometry and there are a range of C-H⋯O contacts in the crystal structure.

Comparison of the liquid-crystalline properties of a pillar[5]arene core functionalized with 10 mesogenic cyanobiphenyl units with those of a corresponding model compound revealed the strong influence of the macrocyclic pillar[5]arene core on the mesomorphic properties.

The title compound, C(60)H(76)Cl(4)O(12), has a macrocyclic structure and both the upper and lower rim have disordered atoms. There are no hydrogen bonds or π-π stacking inter-actions in the crystal.

A room-temperature ionic liquid containing macrocyclic compound pillar[5]arene in its core was synthesized. The ionic liquid showed high thermal stability, moderate ionic conductivity and solvent-free complexation ability with the guest tetracyanoethylene.

P-glycoprotein, encoded by the multidrug resistance gene MDR1, is an ATP-driven drug efflux pump which is highly expressed at the blood-brain barrier of vertebrates. Drug efflux of macrocyclic lactones by P-glycoprotein is highly relevant for the therapeutic safety of macrocyclic lactones, as thereby GABA-gated chloride channels, which are confined to the central nervous system in vertebrates, ...

Reaction between 4-aminopyridine and a dinuclear zinc(II) component of a Robson macrocyclic ligand has resulted in the formation of a molecular ladder element motif. X-ray single crystal structural analysis indicates that two pyridine rings are assembled at the same direction of the macrocycle, which are placed in a nearly parallel way via pi-pi interactions, forming a concavity structure with ...

In this paper, the structure of a new 16-membered macrocyclic Schiff base compound N,N′-(3,3′-dimethoxy-2,2′-(propane-1,3-diyldioxy)dibenzylidene)propane-1,3-diamine, C22H26N2O4 (1), derived from 1,3-propanediamine and 3,3′-dimethoxy-2,2′-(propane-1,3-diyldioxy)dibenzaldehyde has been studied by single crystal X-ray diffraction, DFT calculations at B3LYP/6-31G** and FT-IR spectroscopy. The titl...

Plasmodium falciparum proteasome (Pf20S) inhibitors are active against at multiple stages—erythrocytic, gametocyte, liver, and gamete activation stages—indicating that selective Pf20S possess the potential to be therapeutic, prophylactic, transmission-blocking antimalarials. Starting from a reported compound, we developed noncovalent, macrocyclic peptide inhibitor of malarial with high species ...