Accumulating evidence indicates that the cellular microenvironment plays a key role in follicular lymphoma (FL) pathogenesis, both within tumor lymph nodes (LNs) and in infiltrated bone marrow where ectopic LN-like reticular cells are integrated within malignant B-cell nodular aggregates. In normal secondary lymphoid organs, specific stromal cell subsets provide a highly specialized microenviro...

Oral lichen planus (OLP) is a chronic inflammatory and immune-mediated disease that presents as bilateral, symmetrical oral lesions with three main clinical presentations: reticular, atrophic, erosive. It clinically characterized by pain, burning sensation, discomfort for sufferers. Currently OLP classified potentially malignant disorder. has been associated numerous systemic connotations such ...

original article   evaluation of lymphadenopathy is of clinical significance as the underlying disease may range from a treatable infectious etiology to malignant neoplasm. the aim and objective of the present study was to evaluate palpable lymph nodes of population working in small to medium scale industries represented as group a by fine needle aspiration cytology (fnac) and to compare the re...

Introduction: Anal malignant melanomas are relatively rare tumors. Because of their polypoid structure, they can be confused with benign anorectal diseases. Wide excision and lymph node dissection is recommended especially in including metastasis because it reduces local recurrence. Case report: We performed abdominoperineal resection + bilateral inguinal iliac paraaortic our 77-year-old female...

breast cancer is a major cause of mortality in women due to malignant diseases and is the most prevalent type of cancer in western countries. according to investigations which has been done in iran so far, the prevalence of disease in our country is also very high, therefore complete attention to clinical and pathological findings of this disease would be extremely essential. in this study, the...

background: to evaluate the efficacy of color doppler ultrasound (cdus) in differentiating benign and malignant cervical lymph nodes by detecting differences in blood flow patterns. materials and methods: in this cross‑sectional prospective study, 25 untreated patients with clinical evidence of cervical lymphadenopathy were evaluated. cdus was performed for 80 cervical lymph nodes. the gray sca...

Hematological abnormalities are very common in the course of systemic lupus erythematosus (SLE). Myelofibrosis is a bone marrow disorder in which there is excessive fibrous tissue formation in the bone marrow. Various benign and malignant disorders can cause or be associated with a diffuse increase in the bone marrow reticular tissue. Some diseases such as infections, neoplasms, and autoimmune ...

INTRODUCTION Oral lichen planus (OLP) is one of the most common dermatologic diseases that manifests in the oral cavity. The purpose of this study was to evaluate the association between smoking habits and the clinical subtypes of OLP. METHODS Oral findings and smoking data from 187 charts of OLP patients from an oral medicine clinic was reviewed and compared to data from 76 matched control p...