different types of actinomyces spp isolated from the oral cavity of human in healthy as well as in pathological state. internally it is only found in association with pathological organs. recently actinomyces naeslundii has been isolated from blood culture of a leukemic patient. present studies indicate the association of this microorganism with cells obtained from bone marrow by punction in mo...

Extrafollicular reticulum cells in lymph nodes are heterogeneous. They express cytokeratins, desmin, and/or vimentin as their intermediate filament profile. Using those markers, we undertook an immunohistochemical study of human lymph nodes under various pathologic conditions. Samples included 15 simple reactive lymph nodes, 7 follicular hyperplasia, 1 necrotizing lymphadenitis, 4 tuberculous l...

Within secondary lymphoid tissues, stromal reticular cells support lymphocyte function, and targeting reticular cells is a potential strategy for controlling pathogenic lymphocytes in disease. However, the mechanisms that regulate reticular cell function are not well understood. Here we found that during an immune response in lymph nodes, dendritic cells (DCs) maintain reticular cell survival i...

Eleven cases of histiocytic necrotizing lymphadenitis were studied. Originally four were misdiagnosed as cervical tuberculous lymphadenitis. The characteristic symptoms and signs were local tenderness, fever, leucocytopenia and good prognosis. Antibody to Epstein-Barr virus was elevated in 2 of 3 cases. Biopsy of the affected lymph node was necessary when the differential diagnosis from lymph n...

Enlargement of lymph nodes can be due to a variety of benign and malignant causes. The most common malignant cause is invasive ductal carcinoma, which is usually visualized with mammography. Excluding breast cancer, other causes of abnormal lymph nodes that produce a negative mammogram include lymphoma, metastases from other malignancies, and benign etiologies such as inflammato...

The reticular framework and reticular fibers in the thymus, cervical lymph node, spleen and bone marrow of Wistar rats were studied by transmission electron microscopy and morphometrical method. The reticular framework was usually observed in these organs as a common structure that consisted mainly of the slender cytoplasmic processes of the fibroblastic reticular cells interconnected with tigh...

Transmission electron microscope observation of mouse lymph nodes demonstrated that reticular fibers in the paracortex were invested not only by reticular cells, but occasionally also by migratory cells such as interdigitating cells, macrophages, and lymphocytes. Quantitative analysis of electron micrographs covering wide areas revealed that about 90% of the surface area of the reticular fiber ...

Lymph-borne, soluble factors (e.g., chemokines and others) influence lymphocyte recirculation and endothelial phenotype at high endothelial venules (HEVs) in lymph node cortex. Yet the route lymph-borne soluble molecules travel from the subcapsular sinus to the HEVs is unclear. Therefore, we injected subcutaneously into mice and rats a wide variety of fluorophore-labeled, soluble molecules and ...

the pre.sent rep.or,t describes the morphological and if nod h pron erative aspects of lymph es iii odgkin s disease grown in tissue culture. the development of hodgkin's lymph-nodes grown in vitro seems to depend upon the  a~e of t~e person and the stage of the hodgkin's disease at the time the i h is obtained. ymp - the morphological and the proliferative aspects ('helralcterizi~d of hodgkin'...