myostatin or growth and differentiation factor 8 (gdf8), has been known as the factor causing double muscling phenotypes in which a series of mutations make the myostatin protein inactive, hence disabling it to regulate the deposition of muscle fibre. this phenotype happens with high frequency in a breed of sheep known as the texel. quantitative trait loci (qtl) studies show that a portion of t...

the present study was carried out with the objective of validating linked ssr markers to rf genes and adopting marker assisted selection (mas) for restorer/non-restorer line detection in wild abortive (wa) type of cytoplasmic male sterility (cms). twelve ssr markers reported to be linked to rf genes were analyzed in the mapping population of nedaa/pajouhesh. among these, three markers, namely, ...

Blinatumomab, the bispecific T cell engager, has been demonstrated as the most successful BsAb to date. Throughout the past decade, vector design has great importance for the expression of monoclonal antibody in Chinese hamster ovary (CHO) cells. It has been indicated that expression plasmids based on the elongation factor-1 alpha (EF-1 alpha) gene and DHFR selection marker can be highly effect...

Blinatumomab, the bispecific T cell engager, has been demonstrated as the most successful BsAb to date. Throughout the past decade, vector design has great importance for the expression of monoclonal antibody in Chinese hamster ovary (CHO) cells. It has been indicated that expression plasmids based on the elongation factor-1 alpha (EF-1 alpha) gene and DHFR selection marker can be highly effect...

a study was conducted to identify ssr markers linked to leaf rust resistance genes lr24 and lr28 and to be used for marker-assisted selection (mas) to transfer both genes to a widely cultivated wheat variety mp 3299 under rainfed condition. f2 individuals of the cross mp 3299×nil pbw 343 were used for generating genotypic data employing closely linked scar markers s73719 and s421570 to lr24 and...