A new study by Sennino and colleagues demonstrates that selective VEGF inhibition via the use of an anti-VEGF antibody is sufficient to increase invasion and metastasis in a c-Met-dependent manner. Anti-VEGF therapy induced tumor hypoxia, hypoxia-inducible factor 1α, and c-Met activation in the RIP-Tag2 model of neuroendocrine pancreatic cancer. Selective c-Met inhibition was sufficient to bloc...

background : a single nucleotide variation within  atechol-o-methyl transferase (comt) gene may alter the comt enzyme activity level. polymorphism of val158met in the comt gene has been related to malignancy. in this regard, a study was carried out to find a possible association between the comt gene polymorphism in patients with sporadic prostate cancer (pca) and benign prostatic hyperplasia (...

with the wind permanent flow in the cities, obtaining the minimal pollution in the environment is accessible. different policies have been considered for optimization of cities such as attachment and or reduction of building parts like air-traps, ceiling forms and so on. due to population growth in cities and the increasing need for resettlement these people in the cities, inevitably, to the hi...

با توجه به اهمیت حذف یون استرانسیم موجود در پساب‌­های هسته­ای، کار حاضر ضمن سنتز لیگاندهای هیدروکسی بنزآلدهید پروپیل تری اتوکسی سیلان (Si-HL3(EtO)) و پیریدیل متیلیدین (Si-L3(EtO)) بررسی خصوصیات نانو ذرات سیلیکای اصلاح ­شده این لیگاندها ­عنوان جاذب جامد از محلول آبی پرداخته شد پارامترهایی مانند pH، زمان، جرم جاذب، دما یون‌­های مزاحم مورد آزمایش قرار گرفت. رفتار جذبی جاذ­ب‌­ها نشان داد سطح توانای...

background: methionine has been suggested as the firstlimitingamino acid for milk production in ruminants. it is importanthow to increase milk protein yield and milk fat in dairy ruminants.objectives: this study was set to investigate the effect of rumenprotected methionine (rpmet) on milk composition of lactatingcashmere rayeni goats. methods: 40 healthy singletoncashmere rayeni goats about 3 ...