Metronidazole is used to treat trichomoniasis, bacterial vaginosis, and other diseases. There are controversy aspects about its teratogenicity. A teratogenic agent can alter morphology or subsequent function of the fetus. The aim of this study was to examine an alternative method for the recognition of the mechanism or the bimolecular potential changes in mice fetus caused by Metronidazole usin...

background: methamphetamine (ma) is a potent psychomotor stimulant with high abuse and addictive potential. ma is a neurotoxic drug which is widely abused by females of childbearing age, raising serious public health concerns in terms of exposure of the fetus to the drug. neurotoxic effects of ma on adult are well known, such as dopaminergic nerve terminal degeneration and cell death in regions...

The immune system in the upper reproductive tract (URT) protects against sexually transmitted pathogens, while at same time providing tolerance responses allogenic sperm and developing fetus. uterine environment is also responsive to hormonal variations during estrus cycle, although most likely timing of exposure pathogens breeding when cervix semi-permissive. goal for intrauterine immunization...

Sulfur Mustard (SM) is a chemical warfare agent which was widely used in the World War I and more recently during Gulf war in the early 1980s'. SM is a strong alkylating agent with known mutagenic and carcinogenic effects but only few studies have been published on its teratogenicity. Since SM has been widely used as a chemical weapon by the Iraqi regime against the Iranian soldiers as well as ...

sulfur mustard (sm) is a chemical warfare agent which was widely used in the world war i and more recently during gulf war in the early 1980s'. sm is a strong alkylating agent with known mutagenic and carcinogenic effects but only few studies have been published on its teratogenicity. since sm has been widely used as a chemical weapon by the iraqi regime against the iranian soldiers as well as ...

conclusions tachyzoite of toxoplasma and dna of this parasite were observed in sub mucosa and muscles of the uterus and in the villis of placenta, but not in histological sections of the fetus. therefore, histological and molecular results were consistent. background toxoplasma gondii is an important zoonotic pathogen. vertical transmission of the parasite occurs when females were infected prim...

introduction: decidua as the nearest mother's tissue layer to the fetus which is in direct contact with the embryo has an important role in composing the appropriate microenvironment for protection of allogenic fetus from mother's immune response. in this study the effect of supernatant from culture of decidual cells on dendritic cells regarding the induction of t-cell allogenic proliferation r...

SimunekJ., A. B. Siddique, E. Hegerova: Placental Transfer of Suljamethazine in Mice and Rats. Acta Vet. Brno, 47,1978: 145-151. Placental transfer of sulfamethazine in mice was investigated in the second half of their pregnancy. The transfer was not free but only a part of the drug administered to mothers was found to pass from the maternal circulation to the fetus. Placental transfer of sulfa...

BACKGROUND Methamphetamine (MA) is one of most common illicit drugs which were reported that nearly half of MA consumers are women. MA can cross through placenta and affects pregnancy and fetus development. OBJECTIVE Our aim was to evaluate effects of injected MA on crown-rump length, head and placental circumference, body weight, histological changes and apoptosis in fetus. MATERIALS AND M...