background: early detection is a key to survival for gastric cancer. molecular markers such as mirna (microrna) can have great importance in the early diagnosis of gastric cancer. expression of mir-21 and mir-221 are deregulated in many types of human cancers. this study aimed to investigate the differences in mirna expression patterns within the iranian population. methods: total rna was extra...

results implementation of modern techniques of immune monitoring, allograft function, awareness about the specific infectious and non-infectious disease in each region improves the quality of renal transplantation. conclusions we need to combine the advance scientific vision with local vigilance to achieve the best outcome in renal allograft recipients evidence acquisitions in this process we s...

background: human umbilical cord blood (hucb) is an acceptable and readily accessible source of stem cells. there is an ongoing interest in cord blood stem cell therapies; however, little is known about the possible unfavorable effects of laboratory modifications on the isolated hucb cells. the involvement of mirnas in several biological processes has been shown. the aim of this study was to ev...

objective: the current methods for bladder cancer diagnosis suffer from low sensitivity and specificity. therefore, finding a novel tumor markers with high specificity and sensitivity is of great interest. micrornas (mirna, mir) are small endogenously-produced, non-coding rnas with an important role in regulating gene expression. recent studies show that mirnas expression profiles represent sig...

Circulating microRNAs have been recognized as promising biomarkers for the detection of lung cancer. The objective of this study was to evaluate miR-10b, miR-1 and, miR-30a in the plasma samples of lung cancer patients to confirm any possible relevance in the early detection of lung cancer. Plasma samples from 47 non-small-cell lung cancer patients and 41 cancer-free subjects were evaluated for...

objective(s): the purpose of this study was to conduct a meta-analysis on human micrornas (mirnas) expression data of endometriosis tissue profiles versus those of normal controls and to identify novel putative diagnostic markers. materials andmethods: pubmed, embase, web of science, ovid medline were used to search for endometriosis mirna expression profiling studies of endometriosis. the mirn...

results researchers have reported that mirnas can repress the expression of important cancer-related genes and might be helpful in the diagnosis and treatment of cancer. during the past two decades, numerous studies have shown that mirnas play an essential role in inhibiting hcc via several different pathways. deregulated mirnas may contribute to carcinogenesis, indicating that mirnas can act a...

intoduction: the discovery of micrornas (mirnas), an extensive family of small non-protein-coding rnas, provided an exciting era in cancer research and recent findings have prompted us to revise the traditional concept of cancer. deregulated mirnas   expression influences biological events leading to cancer such as proliferation, differentiation, metastasis and apoptosis. the expression of onco...