Morphea represents a localized form of scleroderma where there is predominant skin involvement, with occasional involvement of subjacent muscles. However, it usually spares the internal organs [1]. Morphea has been associated with several autoimmune diseases like mixed connective tissue disease, dermatomyositis, pemphigus, myasthenia gravis, bullous pemphigoid, systemic sclerosis, Hashimoto’s t...

OBJECTIVE To compare the frequency of genital lichen sclerosus (LS) in patients with morphea with that of control patients. DESIGN A prospective multicenter study. SETTING Four French academic dermatology departments: Strasbourg, Montpellier, Tenon Hospital Paris, and Henri Mondor Hospital Créteil. PATIENTS Patients were recruited from November 1, 2008, through June 30, 2010. Seventy-six ...

BACKGROUND The etiology of morphea is still unknown. Borrelia spp. as a causative agent of morphea has been discussed since 1985, but the relationship remains uncertain. OBJECTIVES We aimed to find the frequency of Borrelia in morphea lesions by polymerase chain reaction (PCR) in northeast of Iran. PATIENTS AND METHODS Sixty six patients with morphea were prospectively included in the prese...

Morphea is an uncommon connective tissue disease with the most prominent feature being thickening or fibrosis of the dermal without internal organ involvement. It is also known as a part of localized scleroderma. Based on clinical presentation and depth of tissue involvement, morphea is classified into several forms, and about two thirds of adults with morphea have plaque type. Overproduction o...

INTRODUCTION Morphea, also referred to as localized scleroderma, is a rare fibrosing skin disorder of undetermined cause. AIM We report our single-center experience with morphea. MATERIAL AND METHODS The study included 53 patients who were diagnosed with morphea by histopathology in our department between 2010 and 2015. Study data were collected retrospectively from the records of morphea p...

BACKGROUND Coxa profunda is commonly viewed as a radiographic parameter that is indicative of pincer-type femoroacetabular impingement, and this finding can impact diagnostic and surgical decision-making. Validation of coxa profunda as a measure of pincer-type femoroacetabular impingement has not been rigorously analyzed. Our hypothesis was that coxa profunda is a very common radiographic findi...

Morphea is a localized form of scleroderma in which there is predominant skin involvement, with occasional involvement of subjacent muscles and usually spares the internal organs. Thyroid dysfunction has been reported in systemic sclerosis but it has been rarely reported in morphea. There are few case reports of plaque-type morphea associated with autoimmune thyroiditis but generalized morphea ...

IFN: interferon ISR: injection site reaction MS: multiple sclerosis INTRODUCTION Morphea, also known as localized scleroderma, is an uncommon fibrosing condition of the skin and underlying tissue. Although the etiology is unknown, morphea is considered an autoimmune condition in which genetic and environmental factors contribute to disease onset. Although most cases are spontaneous, several inc...