introduction: foot-and-mouth disease (fmd) is a highly contagious and economically devastating viral disease of livestock that is categorized in list a of animal diseases by the world organisation for animal health (oie). vaccination is effective against fmd and the vaccine production centers largely use the industrial ultra-filtration and chromatography in order to remove the cellular proteins...

background and aims: accurate and rapid diagnosis is necessary for effective control and prevention of foot-and-mouth disease (fmd). in present study, was evaluated real time reverse transcription-polymerase chain reaction (rrt-pcr) assay along with diagnostic routine methods for the detection of all seven serotypes of fmd virus (fmdv), namely o, c, a, sat1, 2, 3 and asia 1 in biological sample...

foot-and-mouth disease (fmd) is a major cause of endemic outbreaks in livestock in iran. in this study, clinical field samples of foot-and-mouth disease virus were collected from an outbreak in khorasan razavi province during april and august of 2010, and subjected to indirect sandwich elisa and rt-pcr. the viral serotype circulating during the period was confirmed to be type o. the virus was t...

background: foot -and- mouth disease (fmd) is endemic in iran. molecular techniques for diagnosis of persistent infection or carrier animals have shown a potential ability to improve the detection of a low genome copy number in samples. objectives: the purpose of this study is to evaluate the frequency of foot and mouth disease viral carriers in slaughtered sheep in mashhad industrial abattoir ...

BACKGROUND The Gaussia princeps luciferase is used as a stand-alone reporter of transgene expression for in vitro and in vivo expression systems due to the rapid and easy monitoring of luciferase activity. We sought to simultaneously quantitate production of other recombinant proteins by transcriptionally linking the Gaussia princeps luciferase gene to other genes of interest through the foot-a...

Abstract : Foot and Mouth Disease is one of  the important live stocks contagious viral disease caused by Aphtovirus genus ,  that is belong to family RNA virus  picornaviride. The important characteristic of FMD virus is high mutation that give rise to diversity of Antigen in surface of Neutralizing proteins. For this reason FMD virus have 7 distinct serotype and many subtype. Vaccination is o...

foot and mouth disease (fmd) is a highly contagious viral disease of ruminant which causes fever and postule on mouth, hoof and teat. the main purpose of this study was to determine and charachtrize isolated fmd virus from iran between 2005 - 2006, and to compare it with vaccine virus strains. after preparation of samples, serological test for typing of virus was performed. in order to virus is...