PURPOSE Mucoepidermoid carcinoma is the most common primary malignancy of the salivary gland. Mucoepidermoid carcinoma translocated gene 1-mastermind-like gene family (MECT1-MAML2) gene fusion was identified from a recurring t(11;19)(q21;p13) translocation, which is often the sole cytogenetic alteration in this disease. This fusion transcript has been frequently detected in mucoepidermoid carci...

Mucoepidermoid carcinoma is the most common malignant salivary gland tumor, composed of several different cell types, with controversial histogenesis. The aim of this study was to assess the expression of cytokeratins in mucoepidermoid carcinoma, comparing to cytokeratin expression in normal salivary glands, in order to establish a possible correlation between tumor cells immunostaining and muc...

Mucoepidermoid carcinoma is an uncommon tumor of the lung which usually occurs in young individuals without any known risk factor. It is non-small cell lung cancer of salivary gland type. Clinical presentation is often confused with that of bronchial asthma or pneumonia. Computerised tomography of chest and bronchoscopy establish the diagnosis. Most often it is low grade subtype with excellent ...

Mucoepidermoid carcinoma is a locally invasive tumor of the major and minor salivary glands. A 29-year-old male patient reported complaint slow-growing, painless, non-ulcerated palatal swelling. On clinical evaluation, swelling appeared benign; hence, complete excision lesion was carried out under general anesthesia, with closure by reconstruction partial-thickness flap. Healing uneventful. The...

Introduction: Natural killer (NK) cells, of which CD56 is a specific marker, play an important role in host defense against tumors. Cancer stem cells, of which aldehyde dehydrogenase isoform 1 (ALDH1) is an immunohistochemical marker, are a group of tumorigenic cells which are involved in migration and tumor recurrences. We aimed to evaluate the expression of ALDH1 and CD56 in common salivary g...

A small sub-population of cells characterized by increased tumorigenic potential, ability to self-renew and to differentiate into cells that make up the tumor bulk, has been characterized in some (but not all) tumor types. These unique cells, namedcancer stem cells, are considered drivers of tumor progression in these tumors. The purpose of this work is to understand if cancer stem cells play a...

Mucoepidermoid carcinoma (MEC) is one of the most common salivary gland malignancies. As its name implies, MEC is composed of a mixture of cells, including mucus producing, epidermoid or squamous and intermediate cells. It’s the most common malignant tumor in the parotid (60-70% cases). MEC appears mostly as asymptomatic swellings in minor salivary glands, which being the second most common sit...

BACKGROUND The most common malignant salivary gland tumors that affect both adult and children is mucoepidermoid carcinoma. It usually affects both minor and major salivary glands but parotid gland is considering the most common site in which this tumor arises. CD44, a trans-membrane glycoprotein, is an adhesion molecule of cell surface that play a role in the connections between cell-cell and ...

Mucoepidermoid carcinoma of the trachea is a rare tumor. We report an 80-year-old male with mucoepidermoid carcinoma in the upper trachea with invasion of the isthmus of thyroid gland. The patient’s major symptom was dyspnea with coughing. Computed tomography scan showed a protruding mass into the trachea suspected of thyroid cancer. Ultrasonography also revealed the suspicion of an invasive th...