نتایج جستجو برای: multidrug resistance 1 gene

تعداد نتایج: 3830621  

Background & Aims: The efflux pumps play an important role in the development of drug resistance in Klebsiella pneumoniae. The aim of this study was to investigate the antibiotic resistance, and the presence of efflux genes, as well as molecular typing in clinical isolates of Klebsiella pneumoniae. Materials & Methods: In this cross sectional descriptive study, a total of 100 K. pneumoniae iso...

Journal: :archives of pediatric infectious diseases 0
elham davodian department of microbiology, school of paramedical sciences, ilam university of medical sciences, ilam, ir iran; department of microbiology, school of paramedical sciences, ilam university of medical sciences, p. o. box: 6931873911, ilam, ir iran. tel: +98-8413383711, fax: +98-8413383711سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایلام (ilam university of medical sciences) nourkhoda sadeghifard department of microbiology, faculty of medicine, ilam university of medical sciences, ilam, ir iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی ایلام (ilam university of medical sciences) abdolmajid ghasemian department of bacteriology, faculty of medical sciences, tarbiat modares university, tehran, ir iranسازمان اصلی تایید شده: دانشگاه تربیت مدرس (tarbiat modares university) samileh noorbakhsh research center of pediatric infectious diseases, iran university of medical sciences, tehran, ir iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences)

conclusions more than behalf of the wound isolates were esbl positive, and the presence of blaveb-1 was determined in less than half of these isolates. fortunately, resistance to imipenem and meropenem was low. results the majority of the wound isolates were resistant to augmentin (90%, n = 80) and cefpodoxime (87.6%, n = 78). however, the majority was susceptible to imipenem and meropenem. fif...

Journal: :iranian journal of basic medical sciences 0
mahnaz nourbakhsh biotechnology research center, mashhad university of medical sciences, mashhad, iran nanotechnology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran mahmoud reza jaafari nanotechnology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran hermann lage charite´ campus mitte, institute of pathology, charite´platz 1, d-10117 berlin, germany

objective(s): p-glycoprotein (p-gp) is an efflux protein, the overexpression of which has been associated with multidrug resistance in various cancers. although sirna delivery to reverse p-gp expression may be promising for sensitizing of tumor cells to cytotoxic drugs, the therapeutic use of sirna requires effective carriers that can deliver sirna intracellularly with minimal toxicity on targe...

Journal: :jundishapur journal of microbiology 0
mojgan boroumand department of biology science and research branch, islamic azad university, tehran, ir iran shiva irani department of biology science and research branch, islamic azad university, tehran, ir iran seyed davar siadat microbiology research center and department of bacteriology, pasteur institute of iran, tehran, ir iran; microbiology research center and department of bacteriology, pasteur institute of iran, tehran, ir iran. tel: +98-2166968850, fax: +98-2166953311 saied bouzari molecular biology unite, pasteur institute of iran, tehran, ir iran

conclusions antibiotic resistance gene cassettes may be carried on integron or other genetic elements. the purpose of this study was to detect integron or genomic islands involved in antibiotic resistance profile of the isolates of h. influenzae collected in this study. results of the twenty isolates, all (100%) were resistant to clindamycin, chloramphenicol and tetracycline, 95% to amoxicillin...

Journal: :The Journal of antimicrobial chemotherapy 2005
Angelika Miko Karin Pries Andreas Schroeter Reiner Helmuth

OBJECTIVES The objectives of this study were to determine antimicrobial susceptibility and to characterize the molecular mechanisms of multidrug resistance among German food-borne Salmonella isolates of different serovars. METHODS A total of 319 epidemiologically independent multidrug-resistant isolates from German foodstuffs comprising 25 different serovars were tested for their antimicrobia...

A. Derakhshandeh, R. Firouzi S. Heydari S. Mehrshad

Salmonella is one of the most important zoonotic pathogens with many virulence factors playing a major role in its pathogenesis. The aims of this study were to detect spvA, int2 and invC virulence genes of different Salmonella serotypes isolated from various clinical animal and human sources, and to investigate antibiotic resistance patterns among these serotypes. Using a PCR assay, a total of ...

Journal: :jundishapur journal of microbiology 0
bita bakhshi department of bacteriology, faculty of medical sciences, tarbiat modares university, tehran, ir iran; department of bacteriology, faculty of medical sciences, tarbiat modares university, jalal-ale-ahmad ave., tehran, ir iran. tel: +98-2182884558, fax: +98-2182884555 nazanin eftekhari department of biology, faculty of basic science, science and research branch, islamic azad university, tehran, ir iran mohammad reza pourshafie department of bacteriology, pasteur institute of iran, tehran, ir iran

background: integrons are the major reasons of multidrug resistance (mdr) among enteropathogenic bacteria. occurrence of horizontal gene transfer between integron-carrying microorganisms and other enteric bacteria may increase the rate of emergence of integron-associated antibiotic resistance. objectives: the objective of this study was to investigate class 1 integrons among members of enteropa...

Journal: :iranian journal of veterinary research 2014
r. firouzi a. derakhshandeh s. mehrshad s. heydari

salmonella is one of the most important zoonotic pathogens with many virulence factors playing a major role in its pathogenesis. the aims of this study were to detect spva, int2 and invc virulence genes of different salmonella serotypes isolated from various clinical animal and human sources, and to investigate antibiotic resistance patterns among these serotypes. using a pcr assay, a total of ...

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