Background Leg muscle cramps have been identified as the strongest independent predictor of worse quality of life in Australian children with Charcot-Marie-Tooth disease Type 1A (CMT1A) [1]. There is no accepted treatment for cramp in children with CMT and the cause of cramp is not well understood. Potential therapeutic targets should be carefully identified to direct clinical trials of interve...

Pendahuluan: Chronic Kidney Disease (CKD) yang terjadi > 3 bulan dan ditunjukan oleh nilai laju filtrasi glomerulus (GFR) < 15 ml/menit/1,73m2 pada tahap stadium akhir (End Stage Renal (ESRD)) diperlukan terapi pengganti ginjal, yaitu salah satunya hemodialisis. Salah satu permasalahan sering dikeluhkan pasien hemodialisis rutin adalah muscle cramp, biasanya dirasakan jam sebelum selesai ...

We aimed to determine the prevalence and characteristics of muscle cramps in patients with diabetes compared with healthy volunteers. Frequency, severity (using visual analog scale [VAS]), duration, and disability due to muscle cramps were evaluated, as is standard in clinical trials. Information about each patient’s clinical status was collected, including patient demographics, neuropathy (dia...

OBJECTIVE To examine the utility of repetitive nerve stimulation (RNS) in the evaluation of peripheral nerve hyperexcitability (PNH). BACKGROUND PNH describes a group of disorders characterized by muscle cramps, twitching and stiffness. When severe, PNH may be characterized by the presence of continuous muscle fiber activity on routine needle electromyography (EMG). In milder forms of the dis...

33 We analyzed individual motor units during electrically-elicited cramp contractions with 34 the aim of characterizing the variability and degree of common oscillations in their discharges. 35 Intramuscular and surface EMG signals were detected from the abductor hallucis muscle of 11 36 healthy subjects (age 27.0 ± 3.7 yrs) during electrically-elicited cramps. In total, 48 motor units 37 were ...

abstract background: hypotension and muscular cramp are the common complications of hemodialysis. effective control of hemodialysis complications increases the survival time and the quality of life of patients on hemodialysis. considering that failure to follow a therapeutic plan is one of the most prevalent causes of hemodialysis complications, the present research was conducted to study the e...