Background & Aims: Nerve tissue engineering (NTE) is one of the most promising methods for the treatment of the central nervous system (CNS) neurodegenerative diseases. The three-dimensional distribution and growth of the cells within the porous of the scaffold have a significance clinical role in the NTE field. Scaffolds used in tissue engineering, not only must have a good performance, bu...

Background and purpose: One of the recent techniques for increasing the output of cryopreservation is using different scaffolds in long-term preservation of stem cells for cell therapy. Undesirable differentiation and decrease in the number of viable cells are two major problems in this process. In order to overcome these problems, in this study the human amniotic epithelial cells were cryopres...

In this work, poly (hydroxybutyrate co hydroxyvalerate) (PHBV) composite nanofibrous scaffold containing hydroxyapatite/bredigite (HABR) nanoparticles was fabricated through electrospining method. The morphology of prepared  nanofibers and the state of the nanoparticles dispersion in nanofiber matrix were investigated using scanning and transmission electron microscopy, respectively. ...

Background & Aim: The use of bone scaffolds is one of the new and efficient techniques for repairing bone defects that provide a suitable platform for cell proliferation and growth to repair the target tissue. One of the most important causes of failure of transplants and surgical procedures is the invasion of bacteria at the site of the complication and the development of severe infection. The...

Introduction: Poly lactic co- glycolic acid (PLGA) and poly caprolacton (PCL) are highly applicable polymers in the field of drug delivery and tissue engineering scaffolds. Therefore, this study aimed to design an insulin-loaded PCL/PLGA hybrid nanofiber scaffold in order to be applied in attachment and growth of chondrocytes. Moreover, it can provide a vehicle for the controlled release of a...