Aqueous dispersions of hydrophobic high-molar-mass cellulose-graft-polystyrene (Cel-g-PS) copolymers were prepared by nanoprecipitation from dioxane solutions using sodium dodecyl sulfate as a stabilizer. The size and structure of formed Cel-g-PS nanoparticles were studied by scattering techniques (static and dynamic light scattering, SAXS) and transmission electron microscopy. The scattering a...

A derivation of the nanoprecipitation technique without presence surfactants to reduce nanoparticle size is herein proposed. The absence surfactant in allows capturing particles with a smaller diameter than nanoparticles containing surfactants, facilitating migration antioxidant film packaging. Biodegradable PLA clove oil were produced and characterized by dynamic light scattering, zeta potenti...

Although a number of techniques exist for generating structured organic nanocomposites, it is still challenging to fabricate them in a controllable, yet universal and scalable manner. In this work, a microfluidic platform, exploiting superfast (milliseconds) time intervals between sequential nanoprecipitation processes, has been developed for high-throughput production of structured core/shell ...

Poorly water-soluble drugs such as nitrendipine (~2.0 μg/ml at 37C in water) offer challenging problems in drug formulation as poor solubility is generally associated to poor dissolution characteristics and thus to poor oral bioavailability. To enhance these characteristics, we prepared and evaluated nitrendipine nanosuspension using the nanoprecipitation technique. The important process parame...

rivastigmine hydrogen tartrate (rht), one of the potential cholinesterase inhibitors, has received great attention as a new drug candidate for the treatment of alzheimer's disease. however, the bioavailability of rht from the conventional pharmaceutical forms is low because of the presence of the blood brain barrier. the main aim of the present study was to prepare positively charged eudragit r...

Aqueous conjugated polymer nanoparticles developed by nanoprecipitation from a quinoxaline–thiophene type with 3 fluorine atoms as potential cancer theranostics for breast cancer.

Studying the earliest stages of precipitation at the nanoscale is technically challenging but quite valuable as such phenomena reflect important processes such as crystallization and biomineralization. Using a quartz nanopipette as a nanoreactor, we induced precipitation of an insoluble salt to generate oscillating current blockades. The reversible process can be used to measure both kinetics o...

the present work focuses on preparation and characterization of erythromycin loaded gelatin nanoparticles through nanoprecipitation method. the procedure consists of the increase of the aqueous gelatin solution to the non-solvent phase containing lutherol f127. three different measures of cross-linker and polymer concentration were also examined, and the optimum concentration was found. the mor...