A series of bis-naphthalimide derivatives with different diamine linkers were designed and synthesized. All of the synthesized bis-naphthalimide derivatives were characterized by NMR and HRMS spectra. The binding ability between the compounds and CT DNA was evaluated by using UV-Vis titration experiments. The bis-naphthalimide compound with an ethylenediamine linker showed the largest binding c...

In the title naphthalimide derivative, C(23)H(26)N(2)O(6), the 1,8-naphthalimide system is essentially planar [maximum deviation = 0.0456 (16) Å]. A characteristic pattern of alternating long and short C-C bond lengths is observed in the 1,8-naphthalimide unit. The mean planes through the methyl carbamate and acetic acid groups form dihedral angles of 42.30 (9) and 61.59 (9)°, respectively, wit...

A novel fluorogenic probe for tert-butoxy radicals based on the hydrazino-naphthalimide system is reported. Interestingly, different regioisomers exhibited significantly different optical properties toward ROS, which suggested 4-hydrazinyl naphthalimide as a potential new platform for the in vitro and in cellulo detection of alkoxyl radicals.

[reaction: see text] A new fluorescent probe N-butyl-4,5-di[2-(phenylamino)ethylamino]-1,8-naphthalimide 1 senses only Cu(II) among heavy and transition metal (HTM) ions by means of a colorimetric (primrose yellow to pink) method with a large red-shift in emission (green to red) attributed to the deprotonation of the secondary amines as a receptor conjugated to the naphthalimide fluorophore.

In the scope of a Sequential QM-MM approximation [1], we investigated the solvent effect on the conformational and electronic structure of 1-8-Naphthalimide in both ground and excited states. We obtained the optimized structure of 1-8Naphthalimide in acetonitrile, ethanol and water, in ground and in the first excited state. Then we computed the absorption and fluorescence spectra using CASPT2 a...

A 1,8-naphthalimide with [6]helicene derivative scaffold has been designed and synthesized. The (P)- and (M)-enantiomers of the [6]helicene derivative were resolved by HPLC on a chiral column. The single crystal of the [6]helicene derivative exhibits an intermolecular interactions of the 1,8-naphthalimide units.

A series of cyclometalated N-heterocyclic carbene complexes of the general formula [Ir(C^N)2(C^C:)] has been prepared. Two sets of compounds were designed, those where (C^C:) represents a bidentate naphthalimide-substituted imidazolylidene ligand and (C^N) = ppy (3a), F2ppy (4a), bzq (5a) and those where (C^C:) represents a naphthalimide-substituted benzimidazolylidene ligand and (C^N) = ppy (3...

Triarylborane substituted naphthalimide 3 was designed and synthesized by the Sonogashira cross-coupling reaction. The electronic absorption and emission spectra of the triarylborane naphthalimide 3 show red shifted absorption and emission as compared to 4-bromonaphthalimide 2. The sensing behaviour of 3 was studied for different anions. The triarylborane naphthalimide 3 selectively detects F(-...

A series of monoazo disperse dyes based on naphthalimide was synthesized using N-alkylcarboxylic acid-1,8-naphthalimide as diazo component and N,N-diethylaniline derivatives as a coupling components. 4-amino-N-ethanoic (propanoic) acid-1,8-naphthalimide was synthesized from 4-nitro-1,8-naphthalic anhydride by imidation and subsequent reduction reactions. These compounds were diazotized and furt...

The synthesis, spectroscopic characterisation and biological evaluation of mono- and bis-1,8-naphthalimide-conjugated ruthenium(ii)-polypyridyl complexes is presented. Spectroscopic DNA titrations, together with denaturation studies, show strong binding of both species to DNA through the naphthalimide arms. Linear and circular dichroism (LD and CD) spectroscopy reveal close association of the R...