background and aims. recent literature shows that accelerated portland cement (apc) is a non-toxic material that may have potential to promote bone healing. the objective of this study was to histologically evaluate periodontal healing focusing on new bone regeneration following implantation of apc into intra-bony defects in dogs. materials and methods. three-wall intra-bony periodontal defects...

statement of problem: reconstruction methods are an essential prerequisite for functional rehabilitation of the stomatognathic system. platelet-rich plasma (prp) offers a new and potentially useful adjunct to bone substitute materials (e.g. xenografts) in oral and maxillofacial bone and implant reconstructive surgery. purpose: an animal study was carried out to investigate the influence of prp ...

background and aims. autogenous bone graft is commonly used for reconstruction of bone defects in routine surgical procedures. the complexity of producing bone grafts and their application has lead to the use of human bone matrix gelatin (hbmg). the present study was conducted to compare the efficacy of hbmg and autograft on the reconstruction of bone defects in rats. materials and methods. in ...

introduction : efforts are being made to improve the efficacy of biomaterials used as bone substitutes for bone regeneration in the oral and maxillofacial region. graft materials have been recently produced in iran; however, studies are required to confirm their efficacy. this study aimed to compare the histomorphometric results of using mineralized allografts produced by the hamanandsaz baft k...

mandibular defects may result from many conditions such as trauma, inflammatory diseases and tumors. there are rare cases reported in the literature that have demonstrated spontaneous bone regeneration after resection of the mandible. several factors such as age, preservation of the periosteum and genetics seem to influence spontaneous bone regeneration capacity in individuals. evaluation of th...

Background: Repair of bone defects is challenging for reconstructive and orthopedic surgeons. In this study, we aimedto histomorphometrically assess new bone formation in tibial bone defects filled with octacalcium phosphate (OCP),bone matrix gelatin (BMG), and a combination of both.Methods: A total of 96 male Sprague Dawley rats aged 6-8 weeks weighing 120-150 g were randomly allocatedinto thr...

Objective- Bone regeneration is a multifactorial phenomenon which contributed to several factors. It is reported that risedronate is effective for musculoskeletal diseases. The current study was to determine effectiveness of the risedronate-loaded nano capsules for calvaria healing in rabbit.Design- Experimental study.Procedures- 15 white adult male New Zealand rabbits were used. Fo...

both anorganic bovine bone (abb) and β-tricalcium phosphate (β-tcp) are used in clinical practice as bone substitute materials, but there is limited data comparing these two materials in standardized defects. the aim of this study was to histologically evaluate the effectiveness of abb and β-tcp in the healing of experimentally induced bone defects.eighteen bone defects were created on the calv...

background: the aim of this research was to evaluate the effect of adipose derived stem cells on bone repair in through and through mandibular bone defects of canine. materials and methods: in this prospective comparative study, adipose-derived stem cells were isolated from subcutaneous fat of lateral thoracic area of 4 dogs. the isolated cells were cultured and expanded through 3 passages. the...