The only scientifically valid control for such experiments is the concurrent control, not historical control data. This is because scientific experiments are designed to reduce variables to a minimum. The concurrent control group achieves this because it consists of animals treated identically to the experimental group, except that they are not exposed to the substance under study. Thus, the on...

A novel multiplex PCR method was developed for simultaneous event-specific detection of four events of GM maize, i.e., DAS-59122-7, MIR604, MON88017, and MON863. The single laboratory examination of analytical performance using simulated DNA mixtures containing GM DNA at various concentrations in non-GM DNA suggested that the limits of detection (LOD) of the multiplex PCR method were 0.16% for ...

MON 87460 (D1) maize contains a gene that expresses the cold shock protein B (CSPB) from Bacillus subtilis to confer a yield advantage when yield is limited by water availability. This study evaluated the composition of grain from the D1-containing combined-trait maize hybrids D1 × NK603, D1 × MON 89034 × NK603, and D1 × MON 89034 × MON 88017. These stacks offer a combination of insect protecti...

A long-term animal toxicity study claiming adverse effects of genetically engineered (GE) corn 1 has caused an international maelstrom. The study examined how exposure to the herbicide Roundup® and NK603 Roundup Ready® maize (GE corn engineered to withstand glyphosate, the active ingredient in Roundup) affected Sprague-Dawley rats over a 2-year period, roughly equivalent to 65 years in humans. ...

A 2-year rat feeding study with genetically modified NK603 maize sparked an international scientific and public debate as well as policy responses by the European Commission. The European Food Safety Authority (EFSA) evaluated the study as defective based on conceptual and methodological shortcomings by retroactive application of the recommendations of its recent guidance on 90-day feeding stud...

Agronomic characteristics of genetically modified (GM) MON 89034 × TC1507 × NK603 × DAS-40278-9 (PowerCore™ Enlist™), MON 89034 × TC1507 × NK603 (PowerCore™), and DAS-40278-9 (Enlist™) corn, a non-GM near-isogenic hybrid, and 2 commercial non-GM hybrids were assessed in a field study to determine if the agronomic performance of the GM corn hybrids is equivalent to that of non-transgenic hybrid ...

Abstract Objective A systematic review of animal and human studies was conducted on genetically modified (GM) food consumption to assess its safety in terms adverse effects/events inform public concerns future research. Methods Seven electronic databases were searched from January 1st 1983 till July 11th 2020 for vivo, the incidence GM products consumption. Two authors independently identified ...

A comparison was drawn between the effect of glyphosate (Roundup Plus), a post-emergence applied herbicide, and Harness GTZ, a pre-emergence applied herbicide, on the culturable fraction of the rhizobacterial communities of genetically modified NK603 glyphosate-tolerant maize. Two different non-selective rich media were used to grow fast-growing culturable bacteria, BHI and NB, as a more accura...

Small-scale subsistence farmers in South Africa have been introduced to genetically modified (GM) crops for more than a decade. Little is known about i) the extent of transgene introgression into locally recycled seed, ii) what short and long-term ecological and socioeconomic impacts such mixing of seeds might have, iii) how the farmers perceive GM crops, and iv) to what degree approval conditi...

Sixteen multiparous Holstein cows averaging 74 d in milk were used in a replicated 4 x 4 Latin square to compare the effects on animal performance of feeding whole plant silage and grain from a glyphosate-tolerant corn hybrid (event NK603), a nontransgenic control hybrid, and two commercial nontransgenic hybrids (DK647 and RX740). The grain and silage from the four corn hybrids were produced us...