Aging is a major risk factor for several conditions including neurodegenerative, cardiovascular diseases and cancer. Functional impairments in cellular pathways controlling genomic stability, and immune control have been identified. Biomarker of immune senescence is needed to improve vaccine response and to develop therapy to improve immune control. To identify phenotypic signature of circulati...

Lymphocyte subpopulations producing cytokines and exerting regulatory functions represent key immune elements. Given their reciprocal interdependency lymphocyte subpopulations are usually assayed as diagnostic panels, rather than single biomarkers for specialist clinical use. This retrospective analysis on lymphocyte subpopulations, analyzed over the last few years in an outpatient laboratory i...

We propose a new time-release protocol based on the bitcoin protocol and witness encryption. We derive a “public key” from the bitcoin block chain for encryption. The decryption key are the unpredictable information in the future blocks (e.g., transactions, nonces) that will be computed by the bitcoin network. We build this protocol by witness encryption and encrypt with the bitcoin proof-of-wo...

it has been demonstrated that natural killer (nk) cells play a role in regulation of autoimmunity. they play a protective role in several rodent disease models. in this study we aimed to compare the immunophenotypic features of nk cells in ankylosing spondylitis (as) with normal subjects with regard to cd56 and cd16 molecules. this study was carried out on 30 as patients and 33 normal volunteer...

Consider a $2$-nondegenerate constant Levi rank $1$ rigid $\mathscr{C}^{\omega}$ hypersurface $M^5 \subset \mathbb{C}^3$ in coordinates $(z, \zeta, w = u+iv)$: \[ u F(z,\zeta,\overline{z},\overline{\zeta}). \] The Gaussier-Merker model $u \frac{z \overline{z} + \frac{1}{2} z^2 \overline{\zeta} \overline{z}^2 \zeta}{1 - \zeta \overline{\zeta}}$ was shown by Fels-Kaup 2007 to be locally CR-equiva...

In this paper, we extend the construction of a fuzzy subgroup generated by a fuzzy subset to $L$-setting. This construction is illustrated by an example. We also prove that for an $L$-subset of a group, the subgroup generated by its level subset is the level subset of the subgroup generated by that $L$-subset provided the given $L$-subset possesses sup-property.

the term mitral valve prolapse (mvp) is used for a particular subset of patients with hyperadrenergic dysautonomia. it occurs when part of a leaflet or both leaflets of the mitral valve extend above the plane of the atrioventricular junction during ventricular systole. the adenylate cyclase activity in mvp dys-autonomia was studied by extraction of enzyme from the erythrocytes from 62 normal su...

a finite group g is said to be a pos-group if for each x in g the cardinality of the set {y in g | o(y) = o(x)} is a divisor of the order of g. in this paper we study the structure of pos-groups with some cyclic sylow subgroups.