BACKGROUND For the purpose of understanding the Food and Drug Administration's (FDA's) concerns regarding online promotion of prescription drugs advertised directly to consumers, this study examines notices of violations (NOVs) and warning letters issued by the FDA to pharmaceutical manufacturers. METHODS The FDA's warning letters and NOVs, which were issued to pharmaceutical companies over a...

user-generated medical messages on internet contain extensive information related to adverse drug reactions (adrs) and are known as valuable resources for post-marketing drug surveillance. the aim of this study was to find an effective method to identify messages related to adrs automatically from online user reviews.we conducted experiments on online user reviews using different feature set an...

Kim’s overview of Food and Drug Administration (FDA) regulatory actions from 2005 to 2014 is a comprehensive analysis of the US regulatory experience with online direct-to-consumer advertising (DTCA) of prescription medicines. This experience is of relevance internationally as online DTCA reaches the English-speaking public globally, despite the illegality of DTCA in most countries. The most co...

This study is motivated by the premise that online consumers can make a purchase at any time of day if they have even a tiny time slot along with Internet access. Given the increased shopping time flexibility, we first examine the patterns of online purchase timing at an online shopping mall handling diverse products (e.g., Amazon.com). The results show (1) the breakdown of purchase timing regu...

Promotion can stimulate consumer’s unplanned buying which is regarded as the main source of sales growth, however, it may increase consumer’s planned buying shortfall as well. On one hand, online scarce promotion more significantly influences consumer’s unplanned buying and planned buying shortfall; On the other hand, frequent and continuing online promotion weakens its marginal performance. Un...