OBJECTIVE this paper reports an association between an increased Nuchal Translucency (NT) and Osteogenesis Imperfecta (OI), a type of skeletal dysplasia. Measurement of fetal NT at 10-14 weeks of gestation is a sensitive and effective screening method for chromosomal abnormalities. METHODS a 35-year- old Caucasian woman in her fourth pregnancy was referred to our clinic for an ultrasound scan...

INTRODUCTION Zoledronic acid or zo/edronate is a potent bisphosphonate that recently has been used in children with osteoporosis and osteogenesis imperfecta (01), so it could be an option in the treatment of children with this terrible disease that virtually condemns them to a life of pain and prostration. The aim of this study was to evaluate the clinical and biochemical conditions of pediatri...

Mesenchymal stem cells are stem/progenitor cells originated from the mesoderm and can different into multiple cell types of the musculoskeletal system. The vast differentiation potential and the relative ease for culture expansion have established mesenchymal stem cells as the building blocks in cell therapy and tissue engineering applications for a variety of musculoskeletal diseases, includin...

the traditional economic production quantity (epq) model assumes that during the production process no imperfect item is produced. but in the real production system, due to imperfect production process or other factors, imperfect quality items may be produced. furthermore, it is well-known that the total production-inventory costs can be reduced by reworking the imperfect quality items produced...

background with the growing interest in long bone distraction several types of distractors have been introduced; all have the same principle of an outer structure which acts like a scaffold and the distracting mechanism is a separate device which is mounted on this outer structure. objectives we have used a simple and very light weight external fixator we designed and discuss the results of dis...

Osteogenesis imperfecta (OI) is a disease that characterized by hereditary connective tissue dysplasia and clinically manifested as excessive bone fragility limb deformity. The overall incidence of OI 1:10,000-20,000 live births. main autosomal dominant inheritance path, recessive X-linked forms have been established, sporadic cases the disease, denovo mutations familial mosaicism described. 85...

Osteogenesis imperfecta presents with unique challenges to the anaesthetist. We report a case of osteogenesis imperfecta, posted for rush rodding femur managed caudal anaesthesia and sedation dexmedetomidine ketamine.

osteogenesis imperfecta (oi) as an inherited connective tissue disorder can affect all tissues that contains type i collagen. well-known cardiac complications of this disease such as aortic root dilatation, aortic regurgitation and mitral valve prolapse have been rarely reported in the literature. coronary artery aneurysm is a rare cardiac complication in oi, as reported in a 19 year old female...