osteogenesis imperfecta is a rare inherited connective tissue disorder with an expression that varies from mild to severe disease affecting bone, sclera and middle ear. fertility is preserved, especially in those patients with type 1. we present hereby a pregnant woman with osteogenesis imperfecta that had over 30 fractures in long bones and vertebrae. the object of this report was to determine...

This article presents an example of prenatal diagnosis of the IIA (lethal) form of imperfect osteogenesis during the second trimester screening examination. At the parents examination external signs of dysembryogenesis in the father are noticed. The further studying of the case allowed to draw the conclusions about the family form of imperfect osteogenesis when the father of a fetus had mild – ...

Osteogenesis Imperfect (OI) (Brittle Bones Disease) is the most common hereditary connective tissue disease. The main clinical forms of OI are quantitative and qualitative anomalies type I collagen, protein in bones [8]. In modern literature, cases successful delivery patients with imperfect osteogenesis described, however this disease considered a contraindication to pregnancy, when it advised...

Osteogenesis imperfecta is a collagen related disorder characterized by increased bone fragility and low bone mass. The important oral finding in osteogenesis imperfect is the presence of dentinogenesis imperfecta. This article presents a case of osteogenesis imperfecta (type IV B) with dentinogenesis imperfecta where a 7-year-old girl had opalacent primary teeth associated with severe bone def...

Bone fractures are a medical condition where the continuity of the bone is broken due to a fall or accident. The fracture may also be the result of medical conditions such as osteoporosis, cancers of bone or osteogenesis imperfect. During the bone fracture healing process, the mesenchymal stem cells (undifferentiated connective tissue cells) are recruited from local and systemic sources. The mo...