Platelet dynamics in chronic liver disease have been studied using 111Indium-8-hydroxyquinolone (111In-oxine) as a platelet label. In 20 patients, mainly with alcoholic cirrhosis, the platelet mean life span was reduced in 12 and the splenic platelet pool increased, often markedly so, in 15. However, the platelet count was not significantly related to mean bile span, the splenic platelet pool, ...

UNLABELLED Transplantation of progenitor cells (PCs) has been shown to improve neovascularization and left ventricular function after myocardial ischemia. The fate of transplanted PCs has been monitored by fluorescence labeling or by genetic modifications introducing reporter genes. However, these techniques are limited by the need to kill the experimental animal. The aim of this study was to r...

In previous papers of this series (Gale & Folkes, 1955a, b) a description has been given of a preparation of disrupted staphylococcal cells which can be used to study the dependence on nucleic acid of protein-synthesis and amino acid-incorporation reactions. Removal of nucleic acid from the preparation results in marked decrease in the incorporation of certain amino acids; the incorporation can...

1. A detailed laboratory method is described for the labelling of human platelets with [111In]indium oxine. The 45 min method is simple, requires on 26 ml of blood and is suitable for routine clinical use. 2. After the labelling and resuspension of the platelets in plasma, aggregation responses to both adenosine diphosphate and collagen were similar to those of normal platelet-rich plasma. Less...

Complications associated with the vascular access for hemodialysis represent one of the most important causes of morbidity among patients with renal replacement therapy. Early detection of arteriovenous fistula (AVF) dysfunction is of great interest. We present the case of a 70 year old woman who underwent 111In-oxine-labeled-platelet scintigraphy to evaluate thrombogenicity at 3 weeks and 3 mo...

Plant nutrition studies frequently require nearly complete elimination of trace metals from the nutrient media in which the plants are to be grown. Conventional methods of purification by recrystallization and precipitation have been used for this purpose in some studies. These have proved more difficult and less effective than the adsorption technique developed by STEINBERG (11) and improved b...

Some of the major components of a Howe truss bridge, built from durable Australian hardwoods, were treated with preservatives applied to the surface and inserted into holes bored into the components. The preservatives included two copper naphthenate formulations, two formulations based on 2(thiocyanomethylthio) benzothiazeole (TCMTB), two boron-based products and an oxine-copper formulation. Th...

The electronic spectra and the photochemistry of the uranyl complexes UO2 (salophen) and UO2 (oxinate)2 with H2salophen = N,N'-bis(salicylidene)-o-phenylenediamine and oxine = 8hydroxyquinoline were studied. The excited state behavior of both complexes is determined by a low-energy salophen / oxinateÿ to U(VI) ligand-to-metal charge transfer (LMCT) state which is not luminescent but can be reac...

Autoradiography using 1111n-oxine labeled autologous platelets was performed to observe the behavior of platelets in induced vascular injury by activated platelets in rabbit's brain and lung. Cerebrovascular injuries were induced by injection of arachidonic acid (AA) (0.7 mg/kg) into right internal carotid artery. Fourteen animals were pretreated with antiplatelet drug, ti clopidine (200 mg/kg)...