The concept of detection limit was combined with quantum chemical calculations for trace analysis cadmium and lead in aqueous solution using deprotonated 8-hydroxyquinoline (oxine) as ligand. DFT study performed 6-31G(d), cc-pVTZ SDD basis sets combination different theoretical methods such as; B3LYP, MP2 M06L implemented Gaussian 09 program package. obtained results the gas phases show that st...

IT has been shown that 8-hydroxyquinoline is not toxic for Staphylococcus aureus unless traces of iron (or copper) are present in the medium (Rubbo, Albert and Gibson, 1950). It was next shown that a large excess of either iron or oxine prevented a rapid bactericidal action. This led to the hypothesis that oxine gained access to the cells as a complex having one atom of the metal bound between ...

PURPOSE To compare prospectively the accuracy of positron emission tomography (PET) with leukocytes labeled in vitro with (18)F fluorodeoxyglucose (FDG) versus that of conventional scintigraphy with leukocytes labeled in vitro with (111)In oxine in patients suspected of having infection. MATERIALS AND METHODS This HIPAA-compliant study had institutional review board approval; informed consent...

There is considerable disagreement as to whether oxine or tropolone is the best labeling agent for indium leukocytes. We have previously looked at the sensitivity of oxine-labeled 111In leukocyte scans for occult infections and now present a similar group of patients imaged with tropolone-labeled 111In leukocytes. Thirty-four patients (38 studies) with possible occult infection were prospective...

BACKGROUND Quinoline ring has therapeutic and biological activities. Quinolyl hydrazones constitute a class of excellent chelating agents. Recently, the physiological and biological activities of quinolyl hydrazones arise from their tendency to form metal chelates with transition metal ions. In this context, we have aimed to study the competency effect of a phenolic quinolyl hydrazone (H2L; pri...

BACKGROUND A major challenge in the development of cell based therapies for glioma is to deliver optimal number of cells (therapeutic dose) to the tumor. Imaging tools such as magnetic resonance imaging (MRI), optical imaging, positron emission tomography (PET) and single-photon emission computed tomography (SPECT) has been used in cell tracking and/or biodistribution studies. In this study, we...

BACKGROUND Patients with chronic aortic dissection require monitoring for indications of disease progression. In present study, inflammation adjacent to associated aortic wall was evaluated by indium-111-oxine-labeled leukocyte scintigraphy, scince inflammation of the blood vessel wall often associates with progression of chronic aortic dissection. METHODS AND RESULTS Fifteen patients with ao...

Coronary arteriography revealed significant left anterior descending coronary artery stenosis in a 72-year-old man with a history of myocardial infarction. Stenting of the stenotic vessel was performed. Twelve hours after stenting the patient complained of chest pain but emergent coronary arteriography did not show sign of any coronary arterial stenosis. Under suspicion of coronary thrombus for...

There is considerable disagreement as to whether oxine or tropolone is the best labeling agent for indium leukocytes. We have previously looked at the sensitivity of oxine-labeled ln leukocyte scans for occult infections and now present a similar group of patients imaged with tropolone-labeled ln leukocytes. Thirty-four patients (38 studies) with possible occult infection were prospectively stu...