Transdermal drug delivery offers several advantages, including avoidance of erratic absorption, absence of gastric irritation, painlessness, noninvasiveness, as well as improvement in patient compliance. With this mode of drug administration, there is no pre-systemic metabolism and it is possible to increase drug bioavailability and half-life. However, only a few molecules can be delivered acro...

BACKGROUND This study was conducted to ascertain the feasibility of using rapid oral fluid testing as an alternative HIV testing method in China. METHOD This is a mixed-method study among men who have sex with men (MSM), female sex workers (FSW) and VCT clients, conducted in 4 cities in Shandong Province. A pre-tested questionnaire was administered to 1137 participants through face-to-face in...

OBJECTIVE To evaluate the efficacy of the atomized nasal douche in the restoration of physiological nasal functions in patients affected by acute viral rhinosinusitis, when compared with nasal lavages with isotonic sodium chloride solution. DESIGN Randomized clinical trial. SETTING The ENT Department at the University of Siena Medical School. PATIENTS Two hundred patients affected by acut...

Current testing for COVID-19 relies on reverse-transcriptase polymerase chain reaction from a nasopharyngeal swab specimen. Saliva samples have advantages regarding ease and painlessness of collection, which does not require trained staff may allow self-sampling. We enrolled 776 persons at various field-testing sites collected pooled saliva samples. One hundred sixty two had positive RT-PCR, 61...

The subject matter of the article is X-ray images teeth during endodontic operations. goal work to compare developed method segmentation radiograph determine length root canal with electrometric and mathematical methods in practice. uses following methods: principles preparation teeth; determining working (radiological, electrometric); threshold method; bone structures on tomographic images. re...

Pain is a subjective and multidimensional experience, present in the majority of patients undergoing surgical procedures. It can cause suffering, distress and impair quality of life, being associated with emotional, spiritual or personal, social and economic issues of individuals [1]. Due to the need to treat pain as a discomfort in the postoperative period, criteria were defined to assess the ...

Medial tibial stress syndrome (MTSS) is a common problem among athletes and soldiers. There is no proven theory that could explain the pathophysiology of shin splints. The therapies described so far are time-consuming and involve a high risk of relapse. The method according to the fascial distortion model (FDM) addresses local changes in the area of the lower leg fascia. It is suited to reduce ...

Sebaceous carcinoma (SC) is a rare type of cancer that aggressive which develops from the sebaceous glands and can impair patients’ visual acuity. It usually arises periorbital area, commonly affects in eyelid. This study discusses lacrimal gland with endophthalmitis. The patient was 53-year-old Javanese man came chief complaint no vision his left eye, painlessness nowadays, previous medical hi...

Aim . Is the features of microelement composition saliva in diabetes mellitus. Objectives. To perform a systematic analysis modern domestic and foreign literature sources to determine main characteristics saliva, which prospects for its use diagnosis patients with Methodology. The study was based on search original articles specifics mellitus eLibrary, PubMed, Elsevier databases. selection rele...