The overproduction of hydrogen peroxide is implicated in the development of numerous diseases and there is currently great interest in developing contrast agents that can image hydrogen peroxide in vivo. In this report, we demonstrate that nanoparticles formulated from peroxalate esters and fluorescent dyes can image hydrogen peroxide in vivo with high specificity and sensitivity. The peroxalat...

AIMS To evaluate the effects of hydrogen peroxide exposure on the survival and proliferation of cultured lens epithelial cells. METHODS TOTL-86 cells, a line of rabbit lens epithelial cells, were used. The survival and proliferation of TOTL-86 cells were quantified by a rapid colorimetric assay (MTT assay). To determine the effects of hydrogen peroxide, TOTL-86 cells were exposed to different...

Honey and hydrogen peroxide are effective antibacterial agents. The antibacterial activity of honey is mainly attributed to hydrogen peroxide generation that is produced in the honey by the activity of the glucose oxidase (GOX) enzyme. Ziziphus Spina Christi and Acacia spp. honey samples were collected for the study. Hydrogen peroxide was measured using a sensitive enzymatic/colorimetric assay....

hydrogen peroxide, an oxidizing agent used in surgery for its antiseptic properties, has been associated with life-threatening complications. we report a case of suspected gas embolism following irrigation of a tibial bone cyst with hydrogen peroxide in a five year-old boy under general anesthesia, who died despite resuscitative measures and a long stay in the intensive care unit.

The formation of hydrogen peroxide during the oxidation of NADH by purified preparations of cytochrome o has been demonstrated by employing three independent methods: polarographic, calorimetric, and fluorometric. The first two methods were used to assay for the accumulation of hydrogen peroxide and showed that hydrogen peroxide did accumulate as a product, but only about 30% of the oxygen cons...

in the present research, the effect of different peroxide charges and reaction times were investigated inhydrogen peroxide bleaching of mixed old newsprint and old magazine deinked pulp. in thebeginning, mixed recycled papers were pulped using conventional method and then deinked byflotation. in addition, deinked pulps (mixture ratio of 70% onp and 30% omg) were bleached withhydrogen peroxide a...

Lactoperoxidase catalyzes the oxidation of thiocyanate by hydrogen peroxide into hypothiocyanite, a reaction which can protect bacterial and mammalian cells from killing by hydrogen peroxide. The present study demonstrates, however, that lactoperoxidase in the presence of thiocyanate can actually potentiate the bactericidal and cytotoxic effects of hydrogen peroxide under specific conditions, s...

Purpose : To 1) evaluate the embryotoxic effects of hydrogen peroxide on mouse embryo development and 2) examine if pentoxifylline can reverse hydrogen peroxide induced embryotoxicity. Methods : Prospective in vitro study examining the effects of varying concentrations of hydrogen peroxide and pentoxifylline on the blastocyst development rate alone as well as in combination. Results : A dose-de...

A technique utilizing 1H NMR spectroscopy has been developed to measure the concentration of hydrogen peroxide from 10(-3) to 10 M. Hydrogen peroxide produces a peak at around 10-11 ppm, depending upon the interaction between solvent molecules and hydrogen peroxide molecules. The intensity of this peak can be monitored once every 30 s, enabling the measurement of changes in hydrogen peroxide co...