Although the capacity of aluminium to prevent experimental silicosis in animals appears to be well established (Dworski, 1955), there is no adequate evidence at present that it can influence the course of silicosis in man. Moreover, it must be administered to man by inhalation and may not be entirely innocuous itself. Recently Marks, Mason, and Nagelschmidt (1956) have described a method for ev...

We have studied the role of protein tyrosine phosphatases (PTPases) during neuronal differentiation of PC12 cells. Nerve growth factor (NGF), a well-characterized differentiating agent for these cells, led to a decrease in DNA synthesis within 24 h. This was accompanied by a 2- to 3-fold increase in the activity of PTPases, measured as the dephosphorylation of polyacidic or polybasic substrates...

Polar transport of the phytohormone auxin through PIN-FORMED (PIN) auxin efflux carriers is essential for the spatiotemporal control of plant development. The Arabidopsis thaliana serine/threonine kinase D6 PROTEIN KINASE (D6PK) is polarly localized at the plasma membrane of many cells where it colocalizes with PINs and activates PIN-mediated auxin efflux. Here, we show that the association of ...

in this paper, the concept of {sl local base with  stratifiedstructure} in $i$-topological vector spaces is introduced. weprove that every $i$-topological vector space has a balanced localbase with stratified structure. furthermore, a newcharacterization of $i$-topological vector spaces by means of thelocal base with stratified structure is given.

The β subunit of voltage-gated Ca2+ (CaV) channels plays an important role in regulating gating of the α1 pore-forming subunit and its regulation by phosphatidylinositol 4,5-bisphosphate (PIP2). Subcellular localization of the CaV β subunit is critical for this effect; N-terminal-dependent membrane targeting of the β subunit slows inactivation and decreases PIP2 sensitivity. Here, we provide ev...

building pounding occurs between two adjacent buildings with small gap or without sufficient separation distance. it leads to damage buildings during earthquake due to impact. many researchers have investigated building pounding based on impact force reduction and energy dissipation increase, when two buildings collide with each other. in numerical investigations, using specific link element, i...