A novel approach for analysis of structure-activity relationships for sets of active compounds is reported. Molecular similarity relationships are analyzed among compounds with related biological activity based on the evaluation of randomly generated fragment populations. Fragments are randomly generated by iterative bond deletion in molecular graphs and hence depart from those obtained by well...

We develop the analogy between self-gravitating Brownian particles and bacterial populations. In the high friction limit, the self-gravitating Brownian gas is described by the Smoluchowski-Poisson system. These equations can develop a self-similar collapse leading to a finite time singularity. Coincidentally, the Smoluchowski-Poisson system corresponds to a simplified version of the Keller-Sege...

The frequency distribution of surnames turns out to be a relevant issue not only in historical demography but also in population biology, and especially in genetics, since surnames tend to behave like neutral genes and propagate like Y chromosomes. The stochastic dynamics leading to the observed scale-invariant distributions has been studied as a Yule process, as a branching phenomenon and also...

Body armor worn by soldiers adversely affects the performance of some physical tasks. These restrictions may also affect the ability to “self-reach” to locations on their own bodies or on their body borne gear. This paper describes the development of laboratory methods to quantify selfreach capability and the results of pilot testing. Participants rated the perceived difficulty of each self-rea...

Aiming at the Present Condition of Research on soybean growth model, in order to recur the overall dynamic process of soybean growth, we parameterized the main factors that can affect the plants’ physical development and built the soybean plant growth model by adopting the classical biologic plant growth logistic equation and the Self-similarity of plant morphology. In VC6.0 environment, we app...

While there has been a growing body of work on word embeddings, and recent directions better reflect sense-level representations, evaluation remains a challenge. We propose a method of query inventory generation for embedding evaluation that recasts the principle of subsumption preservation, a desirable property of semantic graph-based similarity measures, as a comparative similarity measure as...

The caloric curve for mononuclear configurations is studied with a model that allows for both increased surface diffusness and self-similar expansion. The evolution of the effective mass with density and excitation is included in a schematic fashion. The entropies, extracted in a local-density approximation, confirm that nuclei posess a soft mode that is predominately a surface expansion. We al...

Understanding natural language is an inherently complex task for computer algorithms. Crowdsourcing natural language tasks such as semantic similarity is therefore a promising approach. In this paper, we investigate the performance of crowdworkers and compare them to offline contributors as well as to state of the art algorithms. We will illustrate that algorithms do outperform single human con...